Evidence map›Paper›PMID 29707293›Full record

ArticleJournal of thoracic disease2018

A population-based analysis of outcomes after radiotherapy in intensive care unit patients with lung cancer.

Alexander V Louie, Lihua Li, Krista Bray Jenkyn, Britney Allen, George B Rodrigues, Andrew Warner, David A Palma, Salimah Z Shariff

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander V LouieDepartment of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
Lihua LiInstitute for Clinical Evaluative Sciences, London, Ontario, Canada.
Krista Bray JenkynInstitute for Clinical Evaluative Sciences, London, Ontario, Canada.
Britney AllenInstitute for Clinical Evaluative Sciences, London, Ontario, Canada.
George B RodriguesDepartment of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
Andrew WarnerDepartment of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
David A PalmaDepartment of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
Salimah Z ShariffInstitute for Clinical Evaluative Sciences, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the value of radiotherapy (RT) in intensive care unit (ICU) patients with lung cancer is of uncertain efficacy, we evaluated characteristics, outcomes and RT utilization for such patients in Ontario, Canada.

methodsMultiple administrative databases were linked deterministically using unique encoded identifiers to identify eligible patients between April 1, 2007, and March 31, 2014. Differences in patient, treatment, institution and tumor characteristics between RT and non-RT groups at the level of episode of care were compared. Overall survival (OS) was evaluated using the Kaplan-Meier method, with differences compared using the log-rank test. Univariable and multivariable Cox proportional hazard modeling were performed to assess the effect of RT on survival.

resultsRT was delivered in 133 episodes of care to 1.0% (n=131) of the 13,739 unique patients with lung cancer. RT delivery was associated with younger age (median 65

conclusionsMajor geographic disparities exist in the rare use of RT for lung cancer in the ICU. A significant proportion of patients receiving RT achieve discharge and a minority achieve prolonged survival, suggesting that RT use may not be futile.

Indexed as

intensive care unit (ICU)lung neoplasms (cancer)Radiotherapy (RT)survival

Identifiers

PMID29707293
PMCPMC5906249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.