ArticleJRSM open2018
A quantitative analysis of antipsychotic prescribing trends for the treatment of schizophrenia in England and Wales.
Article in JRSM open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk of renal impairment in atypical antipsychotics: a systematic review and meta-analysis.European journal of clinical pharmacology · 2024Pooled it
- Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis.PLoS medicine · 2022Pooled it
- Antipsychotic prescribing trends in England: role of regional disparities, health inequalities and ethnic density.BJPsych open · 2026Article
- Reporting of oral chemical restraint in the Mental Health Services Monthly Statistics for England.BJPsych bulletin · 2026Article
- Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022.Family practice · 2025Article
- Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour.Biological reviews of the Cambridge Philosophical Society · 2025Review
- From Idealist to Realist-Designing and Implementing Shared Decision-Making Interventions in the Choice of Antipsychotic Prescription in People Living with Psychosis (SHAPE): A Realist Review.Schizophrenia bulletin · 2025Review
- Antipsychotic management in general practice: serial cross-sectional study (2011-2020).The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- Article
- Prevalence and Cost of Antipsychotic Prescribing, within the Context of Psycholeptic Prescribing, in the Irish Setting.Healthcare (Basel, Switzerland) · 2024Article
- Antipsychotic quetiapine alters the mouse fecal resistome by impacting antibiotic efflux, cell membrane, and cell wall synthesis genes.Microbiology spectrum · 2024Article
- Management of antipsychotics in primary care: Insights from healthcare professionals and policy makers in the United Kingdom.PloS one · 2024Article
- Five-year trend of antipsychotic prescription practices in a district Hospital in Ghana: A retrospective study.Neuropsychopharmacology reports · 2023Article
- Clinical Presentation and Management of Acute Dystonia from Drug Abuse or Misuse in Adolescents and Young Adults: A Retrospective Cohort Study in Bangkok, Thailand.Emergency medicine international · 2023Article
- Adherence to Typical Antipsychotics among Patients with Schizophrenia in Uganda: A Cross-Sectional Study.Schizophrenia research and treatment · 2023Article
- The Atypical Antipsychotic Quetiapine Promotes Multiple Antibiotic Resistance in Escherichia coli.Journal of bacteriology · 2022Article
- Analysis of the prescription pattern of psychotropics in an outpatient department of a general hospital psychiatry unit.Medical journal, Armed Forces India · 2022Article
- Systemic medicines taken by adult special care dental patients and implications for the management of their care.British dental journal · 2021Review
- Worth the Weight? Olanzapine Prescribing in Schizophrenia. A Review of Weight Gain and Other Cardiometabolic Side Effects of Olanzapine.Frontiers in psychiatry · 2021Article
- Links between the amount of antipsychotic medication prescribed per population at general practice level, local demographic factors and medication selection.BMC psychiatry · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to assess the current antipsychotic prescribing trends for the treatment of schizophrenia and to compare them with available guidelines and research evidence.
designAn observational retrospective quantitative analysis.
settingData were collected from the prescribing cost analysis for the period between 2007 and 2014, including all drugs from the British National Formulary 4.2.1 and 4.2.2. Prescriptions were included from primary and secondary healthcare settings in England and Wales.
participantsNone.
main outcome measuresDefined daily doses of antipsychotics were used to compare popularity of individual drugs and classes of antipsychotics.
resultsThere is a consistent increase in the proportion of atypical antipsychotics prescribed, compared to typical antipsychotics, between 2007 and 2014, with atypicals accounting for 79.9% of total antipsychotics prescribed in 2014.
conclusionThe consistent popularity of atypical antipsychotics is not concordant with the current National Institute for Health and Care Excellence guidelines for the treatment of schizophrenia or the most recent research evidence.
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Registered trials
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