ArticleOncotarget2018
Aloe-emodin as drug candidate for cancer therapy.
Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 62 citations in OpenAlex.
- Advancements in pharmaceutical research on traditional Chinese medicine-metal complexes.Journal of pharmaceutical analysis · 2026Review
- Comprehensive analysis of VDAC1 in gynecological tumors and structure-based virtual screening of its natural inhibitors.Medical oncology (Northwood, London, England) · 2025Article
- Structure-activity relationship of anticancer drug candidate quinones.Turkish journal of chemistry · 2024Article
- The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells.Cell biology and toxicology · 2023Article
- Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.Acta pharmacologica Sinica · 2023Article
- Varietal Differences in Juice, Pomace and Root Biochemical Characteristics of Four Rhubarb (Biotech (Basel (Switzerland)) · 2023Article
- Anticancer action of naturally occurring emodin for the controlling of cervical cancer.Exploration of targeted anti-tumor therapy · 2023Review
- Investigation of the Interaction between Aloe vera Anthraquinone Metabolites and c-Myc and C-Kit G-Quadruplex DNA StructuresInternational journal of molecular sciences · 2022Article
- Peptide-Mediated Targeted Delivery of Aloe-Emodin as Anticancer Drug.Molecules (Basel, Switzerland) · 2022Article
- Advances in Understanding the Role of Aloe Emodin and Targeted Drug Delivery Systems in Cancer.Oxidative medicine and cellular longevity · 2022Review
- Molecular mechanisms and associated cell signalling pathways underlying the anticancer properties of phytochemical compounds fromExperimental and therapeutic medicine · 2021Review
- Article
- Marine Anthraquinones: Pharmacological and Toxicological Issues.Marine drugs · 2021Review
- Aloe and its Effects on Cancer: A Narrative Literature Review.The East African health research journal · 2021Review
- Antibacterial Activity and Membrane-Targeting Mechanism of Aloe-Emodin AgainstFrontiers in microbiology · 2021Article
- Mitochondrial Targeting in an Anti-Austerity Approach Involving Bioactive Metabolites Isolated from the Marine-Derived FungusMarine drugs · 2020Article
- Induction of Apoptosis, Autophagy and Ferroptosis byMolecules (Basel, Switzerland) · 2020Article
- Chemopreventive Property of Sencha Tea Extracts towards Sensitive and Multidrug-Resistant Leukemia and Multiple Myeloma Cells.Biomolecules · 2020Article
- Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.Theranostics · 2020Article
- Antiglycation Activity and HT-29 Cellular Uptake of Aloe-Emodin, Aloin, andMolecules (Basel, Switzerland) · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a leading cause of global mortality, cancer frequently cannot be cured due to the development of drug resistance. Therefore, novel drugs are required. Naturally occurring anthraquinones are mostly present in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.