Evidence map›Paper›PMID 29706962›Full record

ArticleFrontiers in immunology2018

Variable Domain

Fleur S van de Bovenkamp, Ninotska I L Derksen, Mariëlle J van Breemen, Steven W de Taeye, Pleuni Ooijevaar-de Heer, Rogier W Sanders, Theo Rispens

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Reengineered Anti-CD4 Cys-diabody Variants forMolecular imaging and biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Role of B Cell and T Cell Glycosylation in Systemic Lupus Erythematosus.International journal of molecular sciences · 2023
    Review
  16. Glycobiology of rheumatic diseases.Nature reviews. Rheumatology · 2023
    Review
  17. Article
  18. Review
  19. Impact of N-Linked Glycosylation on Therapeutic Proteins.Molecules (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Fleur S van de BovenkampSanquin Research, Department of Immunopathology, Amsterdam, Netherlands.
Ninotska I L DerksenSanquin Research, Department of Immunopathology, Amsterdam, Netherlands.
Mariëlle J van BreemenAcademic Medical Centre, Department of Medical Microbiology, University of Amsterdam, Amsterdam, Netherlands.
Steven W de TaeyeSanquin Research, Department of Immunopathology, Amsterdam, Netherlands.
Pleuni Ooijevaar-de HeerSanquin Research, Department of Immunopathology, Amsterdam, Netherlands.
Rogier W SandersAcademic Medical Centre, Department of Medical Microbiology, University of Amsterdam, Amsterdam, Netherlands.
Theo RispensSanquin Research, Department of Immunopathology, Amsterdam, Netherlands.
Sanquin · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G (IgG) can contain

Indexed as

AntigensB-LymphocytesHumansImmunoglobulin Fab FragmentsImmunoglobulin GPolysaccharidesProtein DomainsProtein StabilityProtein UnfoldingAntigensImmunoglobulin Fab FragmentsImmunoglobulin GPolysaccharidesadalimumabantibody stabilityFab glycosylationIVIgthermal unfoldingvariable domain glycosylation

Identifiers

PMID29706962
PMCPMC5906590
OpenAlexW2796468517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.