ArticleFrontiers in neurology2018
Interaction of Sex and Diabetes on Outcome After Ischemic Stroke.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Ischemic Stroke Mortality in Type 2 Diabetes in the U.S.: National Trends and Demographic Disparities From 1999 to 2019.Endocrinology, diabetes & metabolism · 2025Article
- Gender Predicts Differences in Acute Ischemic Cardioembolic Stroke Profile: Emphasis on Woman-Specific Clinical Data and Early Outcome-The Experience of Sagrat Cor Hospital of Barcelona Stroke Registry.Medicina (Kaunas, Lithuania) · 2024Article
- Temporal trends of ischemic stroke attributable to high fasting plasma glucose in China from the global burden of disease study 2019.Frontiers in endocrinology · 2024Article
- Age at menarche, age at menopause, reproductive years and risk of fatal stroke occurrence among Chinese women: the Guangzhou Biobank Cohort Study.BMC women's health · 2021Article
- Sex-Related Disparities in the Incidence and Outcomes of Ischemic Stroke among Type 2 Diabetes Patients. A Matched-Pair Analysis Using the Spanish National Hospital Discharge Database for Years 2016-2018.International journal of environmental research and public health · 2021Article
- Women With Cerebral Infarction Feature Worse Clinical Profiles at Admission but Comparable Success to Men During Long-Term Inpatient Neurorehabilitation.Frontiers in aging neuroscience · 2021Article
- Functional Disability After Ischemic Stroke: A Community-Based Cross-Sectional Study in Shanghai, China.Frontiers in neurology · 2021Article
- Impact of Diabetes on Complications, Long Term Mortality and Recurrence in 608,890 Hospitalised Patients with Stroke.Global heart · 2020Article
- Association of prestroke glycemic status with stroke mortality.BMJ open diabetes research & care · 2020Article
- NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes.Journal of neuroinflammation · 2019Review
- Age and Sex Are Critical Factors in Ischemic Stroke Pathology.Endocrinology · 2018Review
- Exploring Gender-Specific Stroke Risks in Diabetic Patients: Insights from a Retrospective Analysis of Contributing Factors.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between ischemic stroke (IS), diabetes mellitus (DM), and sex is intriguing. The aim of this study was to assess the effect modification of sex in the association between DM and short- and long-term disability and mortality in first-ever IS patients.
methodsIn a retrospective, observational, hospital-based study of a prospective series including first-ever IS patients from January 2006 until July 2011, differences in 3-month and 5-year mortality, and disability between diabetic and non-diabetic patients [modified Rankin Scale (mRS) from 3 to 5] were analyzed by sex.
resultsIn total, 933 patients (36.3% with DM, 50.5% women) were included. Overall 3-month and 5-year mortality were 150 (16.1%) and 407 (44.1%), respectively. Adjusted for age, previous mRS, and stroke severity, patients with DM had significantly higher 3-month disability [hazard ratio (HR): 1.49 (95% confidence interval (CI): 1.39-1.70),
conclusionSex has a modifier effect on mortality in first-ever IS diabetic patients. Long-term mortality is increased in diabetic women compared with non-diabetic women, a difference not observed in men.
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