Evidence map›Paper›PMID 29706896›Full record

ArticleFrontiers in physiology2018

Modulation of Connexin-36 Gap Junction Channels by Intracellular pH and Magnesium Ions.

Lina Rimkute, Tadas Kraujalis, Mindaugas Snipas, Nicolas Palacios-Prado, Vaidas Jotautis, Vytenis A Skeberdis, Feliksas F Bukauskas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 5 countries.

Lina RimkuteInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Tadas KraujalisInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Mindaugas SnipasInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Nicolas Palacios-PradoCentro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, Valparaíso, Chile.
Vaidas JotautisInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Vytenis A SkeberdisInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Feliksas F BukauskasInstitute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lithuanian University of Health Sciences · LTKaunas University of Technology · LTPontificia Universidad Católica de Chile · CLUniversity of Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Connexin-36 (Cx36) protein forms gap junction (GJ) channels in pancreatic beta cells and is also the main Cx isoform forming electrical synapses in the adult mammalian brain. Cx36 GJs can be regulated by intracellular pH (pH

Indexed as

cell cultureconnexin-36gap junctionsintracellular pH and Mg2+mutants

Identifiers

PMID29706896
PMCPMC5906587
OpenAlexW2797052767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.