ReviewFrontiers in neuroscience2018
Is There Evidence for a Rostral-Caudal Gradient in Fronto-Striatal Loops and What Role Does Dopamine Play?
Review in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Moral decision making under modafinil: a randomized placebo-controlled double-blind crossover fMRI study.Psychopharmacology · 2019Trial
- Aberrant recruitment of the striatum and insula is associated with recalling and suppressing fatigue- and anger-related memories in people with chronic fatigue syndrome/myalgic encephalomyelitis.Brain communications · 2026Article
- Molecular Pathways Potentially Involved in Hallucinatory Experiences During Sleep Paralysis: The Emerging Role of β-Arrestin-2.International journal of molecular sciences · 2025Review
- Beta Oscillations in Monkey Striatum Encode Reward Prediction Error Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Pedunculopontine-induced cortical decoupling as the neurophysiological locus of dissociation.Psychological review · 2023Article
- Individualized Functional Subnetworks Connect Human Striatum and Frontal Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Topographic organization of the human caudate functional connectivity and age-related changes with resting-state fMRI.Frontiers in systems neuroscience · 2022Article
- Prefrontal corticotropin-releasing factor neurons impair sustained attention via distal transmitter release.The European journal of neuroscience · 2021Article
- Differential Effects of Pergolide and Bromocriptine on Working Memory Performance and Brain Activation after Mild Traumatic Brain Injury.Journal of neurotrauma · 2021Article
- Distinct Oscillatory Dynamics Underlie Different Components of Hierarchical Cognitive Control.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Psychotherapy in pain management: New viewpoints and treatment targets based on a brain theory.AIMS neuroscience · 2020Article
- Strategies for the Treatment of Parkinson's Disease: Beyond Dopamine.Frontiers in aging neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Research has shown that the lateral prefrontal cortex (LPFC) may be hierarchically organized along a rostral-caudal functional gradient such that control processing becomes progressively more abstract from caudal to rostral frontal regions. Here, we briefly review the most recent functional MRI, neuropsychological, and electrophysiological evidence in support of a hierarchical LPFC organization. We extend these observations by discussing how such a rostral-caudal gradient may also exist in the striatum and how the dopaminergic system may play an important role in the hierarchical organization of fronto-striatal loops. There is evidence indicating that a rostral-caudal gradient of dopamine receptor density may exist in both frontal and striatal regions. Here we formulate the hypothesis that dopamine may be an important neuromodulator in hierarchical processing, whereby frontal and striatal regions that have higher dopamine receptor density may have a larger influence over regions that exhibit lower dopamine receptor density. We conclude by highlighting directions for future research that will help elucidating the role dopamine might play in hierarchical frontal-striatal interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.