Evidence map›Paper›PMID 29706793›Full record

ArticleInternational journal of mass spectrometry2018

An algorithm to correct saturated mass spectrometry ion abundances for enhanced quantitation and mass accuracy in omic studies.

Aivett Bilbao, Bryson C Gibbons, Gordon W Slysz, Kevin L Crowell, Matthew E Monroe, Yehia M Ibrahim, Richard D Smith, Samuel H Payne, Erin S Baker

Open access · greenAbstract read
In one paragraph

Article in International journal of mass spectrometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Aivett BilbaoEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Bryson C GibbonsEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Gordon W SlyszEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Kevin L CrowellEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Matthew E MonroeEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Yehia M IbrahimEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Richard D SmithEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Samuel H PayneEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Erin S BakerEarth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA, USA.
Pacific Northwest National Laboratory · US

Funding

Equipment Supplement Request for a Research Resource for Ultra-sensitive High Throughput ProteomicsP41GM103493 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SMITH, RICHARD D · 2012 to 2022
$22.6M
Platform Providing Increased Throughput, Sensitivity and Specificity for MetaboloR01ES022190 · NIEHS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI BAKER, ERIN S · 2012 to 2016
$2.2M
NIEHS NIH HHS R01 ES022190NIGMS NIH HHS P41 GM103493
6 · The paper itself

Abstract

The mass accuracy and peak intensity of ions detected by mass spectrometry (MS) measurements are essential to facilitate compound identification and quantitation. However, high concentration species can yield erroneous results if their ion intensities reach beyond the limits of the detection system, leading to distorted and non-ideal detector response (e.g. saturation), and largely precluding the calculation of accurate

Indexed as

Analog-to-digital converter saturationDetector saturationIsotopic envelopeIsotopic ratiosMass spectrometryQuantitationSaturation correction

Identifiers

PMID29706793
PMCPMC5920534
OpenAlexW2767526245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.