ArticleJournal of exposure science & environmental epidemiology2019
Childhood lead biokinetics and associations with age among a group of lead-poisoned children in China.
Article in Journal of exposure science & environmental epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Household interventions for secondary prevention of domestic lead exposure in children.The Cochrane database of systematic reviews · 2020Pooled it
- Portable Cd-109/CZT KXRF system for in vivo bone lead measurement: a field-deployable method for assessing cumulative lead exposure.Journal of exposure science & environmental epidemiology · 2026Article
- Observed and predicted long-term clearance of lead from the blood of children.Journal of toxicology and environmental health. Part A · 2026Article
- The effect of chelation on bone Pb stores in Pb poisoned children.Journal of exposure science & environmental epidemiology · 2025Article
- Dosimetry Testing for a New In Vivo X-ray Fluorescence Measurement System.Health physics · 2025Article
- Bone lead measurements of live condors in field to assess cumulative lead exposure.Environmental science and pollution research international · 2024Article
- Identifying periods of heightened susceptibility to lead exposure in relation to behavioral problems.Journal of exposure science & environmental epidemiology · 2022Article
- A novel calibration for L-shell x-ray fluorescence measurements of bone lead concentration using the strontium KPhysiological measurement · 2021Article
- Lead exposure and association with angiogenic factors and hypertensive disorders of pregnancy.Pregnancy hypertension · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Childhood lead exposure has been shown to have a significant effect on neurodevelopment. Many of the biokinetics involved with lead biomarkers in children still remain unknown. Two hundred fifty (157 in the exposed group and 93 controls) children were enrolled in our study and lead exposed children returned for multiple visits for measurement of blood and bone lead and chelation treatment. We demonstrated that the correlation between blood and bone lead increased with subsequent visits. We calculated the blood lead half-life for 50 patients, and found a significant (p-value < 0.001) positive correlation with age. For ages 1-3 years (N = 17), the blood lead half-life was found to be 6.9 ± 4.0 days and for 3+ years it was found to be (N = 33) 19.3 ± 14.1 days. In conclusion, the turnover of lead in children is faster than in adults. Our results indicate that blood lead is a more acute biomarker of exposure than previously thought, which will impact studies of children's health using blood lead as a biomarker.
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Registered trials
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