Evidence map›Paper›PMID 29705958›Full record

ArticleApplied microbiology and biotechnology2018

Effects of transcriptional mode on promoter substitution and tandem engineering for the production of epothilones in Myxococcus xanthus.

Xin-Jing Yue, Xiao-Wen Cui, Zheng Zhang, Wei-Feng Hu, Zhi-Feng Li, You-Ming Zhang, Yue-Zhong Li

Open access · hybridAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Heterologous production of epothilones inSynthetic and systems biotechnology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Recent Advances in the Synthetic Biology of Natural Drugs.Frontiers in bioengineering and biotechnology · 2021
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xin-Jing YueState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
Xiao-Wen CuiState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
Zheng ZhangState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
Wei-Feng HuState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
Zhi-Feng LiState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
You-Ming ZhangState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China.
Yue-Zhong LiState Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, 250100, China. lilab@sdu.edu.cn.
State Key Laboratory of Microbial TechnologyShandong University · CN

Funding

Key Program of Shandong Natural Science Foundation ZR2016QZ002National Natural Science Foundation of China 31370123National Natural Science Foundation of China 31471183National Natural Science Foundation of China 31670076
6 · The paper itself

Abstract

Promoter optimization is an economical and effective approach to overexpress heterologous genes and improve the biosynthesis of valuable products. In this study, we swapped the original promoter of the epothilone biosynthetic gene cluster in Myxococcus xanthus with two endogenous strong promoters P

Indexed as

Industrial MicrobiologyTranscription, GeneticEpothilonesMultigene FamilyMyxococcus xanthusPromoter Regions, GeneticEpothilonesEpothilone biosynthesisMyxococcus xanthusPromoterSubstitutionTandem engineeringTranscription mode

Identifiers

PMID29705958
PMCPMC5999154
OpenAlexW2799387676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.