ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018
Factors associated with falls in older adults with cancer: a validated model from the Cancer and Aging Research Group.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025).Journal of evidence-based medicine · 2026Guideline
- Falls among geriatric cancer patients: a systematic review and meta-analysis of prevalence and risk across cancer types.BMC geriatrics · 2025Pooled it
- Falls in older adults with cancer: an updated systematic review of prevalence, injurious falls, and impact on cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Modifiable fall risk factors among older adults with advanced cancer: Secondary analysis of a cluster-randomized clinical trial.Journal of geriatric oncology · 2023Trial
- Communication About Fall Risk in Community Oncology Practice: The Role of Geriatric Assessment.JCO oncology practice · 2022Trial
- Prevalence and incidence of falls in older adults with cancer: a systematic review with meta-analysis.Journal of cancer survivorship : research and practice · 2025Review
- Assessment of Mobility Trajectories Using Wearable Inertial Sensors During Autologous Hematopoietic Cell Transplant.Archives of physical medicine and rehabilitation · 2024Article
- Unipedal stance time is associated with fall outcomes in older chemotherapy-treated cancer survivors: A retrospective study.Journal of geriatric oncology · 2024Article
- Accumulated incidence of falls in people hospitalised with cancer and related factors.Nursing open · 2023Article
- Incidence of falls and fall-related injuries and their predictive factors in frail older persons with cancer: a multicenter study.BMC geriatrics · 2022Observational
- Risk factors for falls in hospitalized patients with cancer: A systematic review and meta-analysis.Asia-Pacific journal of oncology nursing · 2022Review
- Polypharmacy, chemotherapy receipt, and medication-related out-of-pocket costs at end of life among commercially insured adults with advanced cancer.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2022Article
- Development of the Exercise in Cancer Evaluation and Decision Support (EXCEEDS) algorithm.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Review
- Bortezomib in first-line therapy is associated with falls in older adults with multiple myeloma.Journal of geriatric oncology · 2021Article
- Expanding Beyond Maximum Grade: Chemotherapy Toxicity over Time by Age and Performance Status in Advanced Non-Small Cell Lung Cancer in CALGB 9730 (Alliance A151729).The oncologist · 2021Article
- Lessons Learned from Arti-Collaborating to Improve Care: the Past, Present, and Future of the Cancer and Aging Research Group.Journal of the American Geriatrics Society · 2019Review
- A Practical Guide to Geriatric Syndromes in Older Adults With Cancer: A Focus on Falls, Cognition, Polypharmacy, and Depression.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2019Review
- Geriatric assessment for the practicing clinician: The why, what, and how.CA: a cancer journal for cliniciansReview
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Authors and funding
17 authors.
Funding
Abstract
backgroundFalls in older adults with cancer are common, yet factors associated with fall-risk are not well-defined and may differ from the general geriatric population. This study aims to develop and validate a model of factors associated with prior falls among older adults with cancer.
methodsIn this cross-sectional secondary analysis, two cohorts of patients aged ≥ 65 with cancer were examined to develop and validate a model of factors associated with falls in the prior 6 months. Potential independent variables, including demographic and laboratory data and a geriatric assessment (encompassing comorbidities, functional status, physical performance, medications, and psychosocial status), were identified. A multivariate model was developed in the derivation cohort using an exhaustive modeling approach. The model selected for validation offered a low Akaike Information Criteria value and included dichotomized variables for ease of clinical use. This model was then applied in the validation cohort.
resultsThe development cohort (N = 498) had a mean age of 73 (range 65-91). Nearly one-fifth (18.2%) reported a fall in the prior 6 months. The selected model comprised nine variables involving functional status, objective physical performance, depression, medications, and renal function. The AUC of the model was 0.72 (95% confidence intervals 0.65-0.78). In the validation cohort (N = 250), the prevalence of prior falls was 23.6%. The AUC of the model in the validation cohort was 0.62 (95% confidence intervals 0.51-0.71).
conclusionIn this study, we developed and validated a model of factors associated with prior falls in older adults with cancer. Future study is needed to examine the utility of such a model in prospectively predicting incident falls.
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