Evidence map›Paper›PMID 29705242›Full record

ArticleThe Journal of allergy and clinical immunology2018

Epithelial barrier dysfunction in desmoglein-1 deficiency.

Laura Polivka, Smail Hadj-Rabia, Elodie Bal, Stéphanie Leclerc-Mercier, Marine Madrange, Yamina Hamel, Damien Bonnet, Stéphanie Mallet, Hubert Lepidi, Caroline Ovaert and 16 more

Open access · greenAbstract readCase ReportsLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. New Insights in Paediatric Dermatopathology-2nd Edition.Dermatopathology (Basel, Switzerland) · 2024
    Article
  11. Dangerous liaisons: Loss of keratinocyte control over melanocytes in melanomagenesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  12. Contribution of Keratinocytes in Skin Cancer Initiation and Progression.International journal of molecular sciences · 2024
    Review
  13. Desmosomes at a glance.Journal of cell science · 2024
    Review
  14. Review
  15. Article
  16. ERBIN and phosphoglucomutase 3 deficiency.Current opinion in immunology · 2023
    Review
  17. Article
  18. Article
  19. Desmosomal Cadherins in Health and Disease.Annual review of pathology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 2 countries.

Laura PolivkaDepartment of Dermatology, Reference Center for Genodermatoses (MAGEC), Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Laboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Smail Hadj-RabiaDepartment of Dermatology, Reference Center for Genodermatoses (MAGEC), Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Laboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Elodie BalLaboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Stéphanie Leclerc-MercierDepartment of Dermatology, Reference Center for Genodermatoses (MAGEC), Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Department of Pathology, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Marine MadrangeLaboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Yamina HamelLaboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Damien BonnetM3C-Necker, Pediatric Reference Center for Inherited Cardiac Diseases, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Stéphanie MalletDepartment of Dermatology, La Timone Hospital (AP-HM), Aix Marseille University, Marseille, France.
Hubert LepidiDepartment of Pathology, La Timone Hospital (AP-HM), Aix Marseille University, Marseille, France.
Caroline OvaertDepartment of Pediatric Cardiology, La Timone Hospital (AP-HM), Aix Marseille University, Marseille, France.
Patrick BarbetDepartment of Pathology, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Christophe DupontDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Bénédicte NevenDepartment of Pediatric Immunology and Hematology, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Arnold MunnichLaboratory of Molecular and Pathophysiological Basis of Cognitive Disorders, U1163, Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Necker-Enfants Malades Hospital, Paris, France.
Lisa M GodselDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Florence CampeottoDepartment of Paediatric Gastroenterology, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Robert WeilLaboratory of Signaling and Pathogenesis, Centre National de la Recherche Scientifique, UMR3691, Pasteur Institute, Paris, France.
Emmanuel LaplantineLaboratory of Signaling and Pathogenesis, Centre National de la Recherche Scientifique, UMR3691, Pasteur Institute, Paris, France.
Sylvie MarchettoCentre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille University, UM105, Inst Paoli-Calmettes, CNRS, UMR7258, Inserm, U1068, "Cell Polarity, Cell Signalling, and Cancer-Equipe Labellisée Ligue Contre le Cancer," Marseille, France.
Jean-Paul BorgCentre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille University, UM105, Inst Paoli-Calmettes, CNRS, UMR7258, Inserm, U1068, "Cell Polarity, Cell Signalling, and Cancer-Equipe Labellisée Ligue Contre le Cancer," Marseille, France.
William I WeisDepartments of Structural Biology, Molecular & Cellular Physiology and Photon Science, Stanford University, Stanford, Calif.
Jean-Laurent CasanovaDepartment of Pediatric Immunology and Hematology, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France; Paris Descartes University, Imagine Institute, Paris, France; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY; Howard Hughes Medical Institute, New York, NY.
Anne PuelLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France; Paris Descartes University, Imagine Institute, Paris, France; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY; Howard Hughes Medical Institute, New York, NY.
Kathleen J GreenDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Christine BodemerDepartment of Dermatology, Reference Center for Genodermatoses (MAGEC), Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France; Laboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France. Electronic address: christine.bodemer@aphp.fr.
Asma SmahiLaboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France. Electronic address: asma.smahi@inserm.fr.
Institut des Maladies Génétiques Imagine · FRUniversité Paris Cité · FRAix-Marseille Université · FRAssistance Publique – Hôpitaux de Paris · FRDélégation Paris 5 · FRInstitut Pasteur · FRNorthwestern University · USInserm · FRStanford University · US

Funding

MOLECULAR GENETICS OF PEMPHIGUS FOLIACEUS ANTIGENR01AR041836 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathleen Janee Green · 1993 to 2026
$11.8M
NIAMS NIH HHS R01 AR041836
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAnimalsCarrier ProteinsCell DifferentiationChildDermatitisDesmoglein 1DesmosomesEpithelial CellsHEK293 CellsHeterozygoteHumansIntracellular Signaling Peptides and ProteinsKeratinocytesMaleMiceCarrier ProteinsDesmoglein 1Erbb2ip protein, mouseIntracellular Signaling Peptides and ProteinsNF-kappa B

Identifiers

PMID29705242
PMCPMC6078820
OpenAlexW2802591971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.