Evidence map›Paper›PMID 29704574›Full record

ReviewNeuroscience letters2019

The intersection of lysosomal and endoplasmic reticulum calcium with autophagy defects in lysosomal diseases.

Elaine A Liu, Andrew P Lieberman

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Contradictory Effects on Hepatocytes in ASMD.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Lysosomes' fallback strategies: more than just survival or death.Frontiers in cell and developmental biology · 2025
    Review
  8. Alterations in Proteostasis Mechanisms in Niemann-Pick Type C Disease.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Review
  11. Ppt1-deficiency dysregulates lysosomal CaJournal of inherited metabolic disease · 2022
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Liver involvement in patients with Gaucher disease types I and III.Molecular genetics and metabolism reports · 2020
    Article
  19. Article
  20. A calcium message for Niemann-Pick type C.The Journal of cell biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elaine A LiuDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, United States; Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI 48109, United States; Cellular and Molecular Biology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Andrew P LiebermanDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, United States. Electronic address: liebermn@umich.edu.

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
CELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8M
Unraveling mechanisms of Niemann-Pick C neuropathology with mouse modelsR01NS063967 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2009 to 2020
$4.4M
NIGMS NIH HHS T32 GM007315NIGMS NIH HHS T32 GM007863NINDS NIH HHS R01 NS063967
6 · The paper itself

Abstract

The lysosomal storage disorders (LSDs) encompass a group of more than 50 inherited diseases characterized by the accumulation of lysosomal substrates. Two-thirds of patients experience significant neurological symptoms, but the mechanisms of neurodegeneration are not well understood. Interestingly, a wide range of LSDs show defects in both autophagy and Ca

Indexed as

AnimalsAutophagyBiological TransportCalciumEndoplasmic ReticulumHomeostasisHumansLysosomal Storage DiseasesLysosomesCalciumAutophagyCalciumEndoplasmic reticulumGaucher diseaseLysosomeNiemann-Pick type C disease

Identifiers

PMID29704574
PMCPMC6202281

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.