Evidence map›Paper›PMID 29704200›Full record

ArticleMolecular neurobiology2019

Identification of Alprenolol Hydrochloride as an Anti-prion Compound Using Surface Plasmon Resonance Imaging.

Yukiko Miyazaki, Takeshi Ishikawa, Yuji O Kamatari, Takehiro Nakagaki, Hanae Takatsuki, Daisuke Ishibashi, Kazuo Kuwata, Noriyuki Nishida, Ryuichiro Atarashi

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Administration of FK506 from Late Stage of Disease Prolongs Survival of Human Prion-Inoculated Mice.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Article
  6. The role of prion strain diversity in the development of successful therapeutic treatments.Progress in molecular biology and translational science · 2020
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yukiko MiyazakiDepartment of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Takeshi IshikawaProgram for Nurturing Global Leaders in Tropical and Emerging Infectious Diseases, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Yuji O KamatariLife Science Research Center, Gifu University, Gifu, Japan.
Takehiro NakagakiDepartment of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Hanae TakatsukiDivision of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Daisuke IshibashiDepartment of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Kazuo KuwataUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan.
Noriyuki NishidaDepartment of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. noriyukinishida@icloud.com.
Ryuichiro AtarashiDivision of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan. ryuichiro_atarashi@med.miyazaki-u.ac.jp.ORCID http://orcid.org/0000-0001-8381-0508
Nagasaki University · JPGifu University · JPUniversity of Miyazaki · JP

Funding

Japan Society for the Promotion of Science JP15H04269
6 · The paper itself

Abstract

Prion diseases are transmissible neurodegenerative disorders of humans and animals, which are characterized by the aggregation of abnormal prion protein (PrP

Indexed as

Imaging, Three-DimensionalAlprenololAnimalsBrainCell Line, TumorMagnetic Resonance SpectroscopyMiceMolecular Docking SimulationOxprenololPrionsProtein BindingPrPSc ProteinsRecombinant ProteinsSurface Plasmon ResonanceSurvival AnalysisAlprenololOxprenololPrionsPrPSc ProteinsRecombinant ProteinsAlprenolol hydrochlorideDocking simulationPrion diseasesSurface plasmon resonance imaging

Identifiers

PMID29704200
OpenAlexW2801283948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.