Evidence map›Paper›PMID 29704108›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Can early palliative care with anticancer treatment improve overall survival and patient-related outcomes in advanced lung cancer patients? A review of the literature.

Massimo Ambroggi, Claudia Biasini, Ilaria Toscani, Elena Orlandi, Raffaella Berte, Martina Mazzari, Luigi Cavanna

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Palliative care interventions for thoracic cancer: a systematic review and meta-analysis identifying the core elements.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Palliative Care in the Ageing European Population: A Cross-Country Comparison.International journal of environmental research and public health · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.Journal of the National Cancer Institute · 2021
    Article
  13. Article
  14. Multidisciplinary team care in advanced lung cancer.Translational lung cancer research · 2020
    Review
  15. Article
  16. Article
  17. How Effective Is Palliative Care in Improving Patient Outcomes?Current treatment options in oncology · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Massimo AmbroggiDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Claudia BiasiniDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Ilaria ToscaniDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Elena OrlandiDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Raffaella BerteDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Martina MazzariDepartments of Pharmacy, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy.
Luigi CavannaDepartments of Oncology-Hematology, Ospedale "G. da Saliceto", via taverna 49, 29121, Piacenza, Italy. l.cavanna@ausl.pc.it.
Guglielmo da Saliceto Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMetastatic non-small-cell lung cancer (NSCLC), the leading cause of death from cancer worldwide, is a debilitating disease that results in a high burden of symptoms and poor quality of life; the estimated prognosis after the diagnosis has been established was less than 1 year until some years ago. At the present, the new targeted therapies and immunotherapy are changing the course of the disease. However, advanced NSCLC remains an incurable disease, with a poor prognosis for the majority of the affected patients, so that quality of life and relief from symptoms are primary objectives of treatment. Some evidences suggest that early palliative care (EPC) for these patients can improve quality of life and even survival.

designA systematic review of the studies evaluating the impact on objective and on patient-reported outcomes of the introduction of EPC in opposition to standard care (SC), for advanced lung cancer patients, was performed. Because of the small number of studies conducted in this area, retrospective studies were also considered for the review.

resultsFive studies were included because they matched the inclusion criteria previously defined as relevant for the study. The review found that both survival and quality of life were better for patients included in EPC groups.

conclusionsWhile results of the studies included in this review are not always comparable because different methods and scales have been used, there is enough evidence for clinical oncologists to implement the use of EPC in clinical practice for advanced lung cancer patients.

Indexed as

Patient Reported Outcome MeasuresFemaleHumansLung NeoplasmsMalePalliative CareQuality of LifeRetrospective StudiesSurvival AnalysisAdvanced lung cancerEarly palliative careQuality of lifeSurvival

Identifiers

PMID29704108
PMCPMC6096526
OpenAlexW2801797122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.