ArticleNature communications2018
Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 103 citations in OpenAlex.
- Microsporidia: evolution, infection mechanisms and host impact.Nature reviews. Microbiology · 2026Review
- The Caenorhabditis elegans microbiome impacts microsporidia infection through nutrient limitation and spore inactivation.Nature communications · 2026Article
- A structural window into the evolution of secondary transport mechanisms.Nature structural & molecular biology · 2025Article
- Article
- Article
- Diatom heterotrophy on brown algal polysaccharides emerged through horizontal gene transfer, gene duplication, and neofunctionalization.PLoS biology · 2025Article
- Host-Parasite Interactions and Integrated Management Strategies for Ecytonucleospora Hepatopenaei Infection in Shrimp.Acta parasitologica · 2025Review
- Determination of protein transporter function using Raman spectroscopy.Microbiology (Reading, England) · 2025Article
- Microsporidia infection alters C. elegans lipid levels.PloS one · 2025Article
- A novel ATP-binding cassette protein (NoboABCG1.3) plays a role in the proliferation of Nosema bombycis.Parasitology research · 2024Article
- Horizontal gene transfer in eukaryotes: aligning theory with data.Nature reviews. Genetics · 2024Review
- Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion.PLoS biology · 2024Article
- Treatment of MicrosporidiumMicroorganisms · 2024Article
- Functional annotation of a divergent genome using sequence and structure-based similarity.BMC genomics · 2024Article
- Nematocida displodere mechanosensitive ion channel of small conductance 2 assembles into a unique 6-channel super-structure in vitro.PloS one · 2024Article
- Single-cell genomics reveals new rozellid lineages and supports their sister relationship to Microsporidia.Biology letters · 2023Article
- Molecular and biochemical changes in Locusta migratoria (Orthoptera: Acrididae) infected with Paranosema locustae.Journal of insect science (Online) · 2023Article
- Germination of Microsporidian Spores: The Known and Unknown.Journal of fungi (Basel, Switzerland) · 2023Review
- An ancient metalloenzyme evolves through metal preference modulation.Nature ecology & evolution · 2023Article
- Genome-wide analysis of transmembrane 9 superfamily genes in wheat (Frontiers in plant science · 2023Article
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11 authors at 3 institutions in 1 country.
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Abstract
The acquisition of genes by horizontal transfer can impart entirely new biological functions and provide an important route to major evolutionary innovation. Here we have used ancient gene reconstruction and functional assays to investigate the impact of a single horizontally transferred nucleotide transporter into the common ancestor of the Microsporidia, a major radiation of intracellular parasites of animals and humans. We show that this transporter provided early microsporidians with the ability to steal host ATP and to become energy parasites. Gene duplication enabled the diversification of nucleotide transporter function to transport new substrates, including GTP and NAD
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