ArticleNature communications2018
Manipulation of insulin signaling phenocopies evolution of a host-associated polyphenism.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- A single-cell atlas of alternative wing development in two hemipteran species.Nature communications · 2026Article
- Aphid wing plasticity: hormonal and epigenetic control mechanisms.Current opinion in insect science · 2026Review
- Opposing insulin signals underlie the same developmental switch across hemipteran insects.Science advances · 2026Article
- Intraspecific microbiome dynamics across the life cycle of the milkweed bugMicrobial genomics · 2026Article
- Mating triggers a physiological switch to reproduction in field crickets to mitigate the flight-oogenesis tradeoff.Current research in insect science · 2026Article
- Molecular mechanisms underlying the evolution of a color polyphenism by genetic accommodation in the tobacco hornworm,Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Insect Flight: State of the Field and Future Directions.Integrative and comparative biology · 2024Article
- Evolution and molecular mechanisms of wing plasticity in aphids.Current opinion in insect science · 2024Review
- The diverse roles of insulin signaling in insect behavior.Frontiers in insect science · 2024Review
- Mitochondria dysfunction impairs Tribolium castaneum wing development during metamorphosis.Communications biology · 2022Article
- Expression Analysis in a Dispersal-Fecundity Polyphenism Identifies Growth Regulators and Effectors.Integrative and comparative biology · 2022Article
- The transcription factor Zfh1 acts as a wing-morph switch in planthoppers.Nature communications · 2022Article
- Photoperiod controls wing polyphenism in a water strider independently of insulin receptor signalling.Proceedings. Biological sciences · 2022Article
- Pea aphid winged and wingless males exhibit reproductive, gene expression, and lipid metabolism differences.Current research in insect science · 2022Article
- Neofunctionalization of a second insulin receptor gene in the wing-dimorphic planthopper, Nilaparvata lugens.PLoS genetics · 2021Article
- Vestigial mediates the effect of insulin signaling pathway on wing-morph switching in planthoppers.PLoS genetics · 2021Article
- RNAi-Based Functional Genomics in Hemiptera.Insects · 2020Review
- Nutrition-responsive gene expression and the developmental evolution of insect polyphenism.Nature ecology & evolution · 2020Article
- Expression profiling of winged- and wingless-destined pea aphid embryos implicates insulin/insulin growth factor signaling in morph differences.Evolution & development · 2020Article
- Insulin signalling's role in mediating tissue-specific nutritional plasticity and robustness in the horn-polyphenic beetle Onthophagus taurus.Proceedings. Biological sciences · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Plasticity, the capacity of an organism to respond to its environment, is thought to evolve through changes in development altering the integration of environmental cues. In polyphenism, a discontinuous plastic response produces two or more phenotypic morphs. Here we describe evolutionary change in wing polyphenism and its underlying developmental regulation in natural populations of the red-shouldered soapberry bug, Jadera haematoloma (Insecta: Hemiptera: Rhopalidae) that have adapted to a novel host plant. We find differences in the fecundity of morphs in both sexes and in adult expression of insulin signaling components in the gonads. Further, the plastic response of ancestral-state bugs can be shifted to resemble the reaction norm of derived bugs by the introduction of exogenous insulin or RNA interference targeting the insulin signaling component encoded by FoxO. These results suggest that insulin signaling may be one pathway involved in the evolution of this polyphenism, allowing adaptation to a novel nutritional environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.