Evidence map›Paper›PMID 29703863›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens.

Yanling Liu, Jonathan R McDaniel, Srijit Khan, Paolo Campisi, Evan J Propst, Theresa Holler, Eyal Grunebaum, George Georgiou, Gregory C Ippolito, Götz R A Ehrhardt

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. B cells in human lymphoid structures.Clinical and experimental immunology · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Immunoglobulin A Glycosylation and Its Role in Disease.Experientia supplementum (2012) · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yanling LiuDepartment of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Jonathan R McDanielDepartment of Molecular Biosciences, College of Natural Sciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0001-8575-3535
Srijit KhanDepartment of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Paolo CampisiDepartment of Otolaryngology-Head and Neck Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada; and.
Evan J PropstDepartment of Otolaryngology-Head and Neck Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada; and.
Theresa HollerDepartment of Otolaryngology-Head and Neck Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada; and.
Eyal GrunebaumDivision of Immunology and Allergy, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada.
George GeorgiouDepartment of Molecular Biosciences, College of Natural Sciences, University of Texas at Austin, Austin, TX 78712.
Gregory C IppolitoDepartment of Molecular Biosciences, College of Natural Sciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-7565-7002
Götz R A EhrhardtDepartment of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; goetz.ehrhardt@utoronto.ca.ORCID 0000-0002-5868-5191
University of Toronto · CAThe University of Texas at Austin · US

Funding

Comprehensive functional assesment of the human antibody response to Enterovirus 71R21AI119368 · NIAID · LANKENAU INSTITUTE FOR MEDICAL RESEARCH · PI DESSAIN, SCOTT KENDALL · 2016 to 2017
$458k
NIAID NIH HHS R21 AI119368
6 · The paper itself

Abstract

FCRL4, a low-affinity IgA Ab receptor with strong immunoregulatory potential, is an identifying feature of a tissue-based population of memory B cells (Bmem). We used two independent approaches to perform a comparative analysis of the Ag receptor repertoires of FCRL4

Indexed as

AntibodiesAntigensB-LymphocytesCell LineGene ExpressionHEK293 CellsHumansImmunoglobulin AImmunologic MemoryLymphocyte ActivationMicrobiotaPhenotypeReceptors, FcAntibodiesAntigensFCRL4 protein, humanImmunoglobulin AReceptors, Fc

Identifiers

PMID29703863
PMCPMC5988966
OpenAlexW2802709264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.