Evidence map›Paper›PMID 29703741›Full record

ReviewHeart (British Cardiac Society)2018

Hyperpolarised magnetic resonance for in vivo real-time metabolic imaging.

Andrew Apps, Justin Lau, Mark Peterzan, Stefan Neubauer, Damian Tyler, Oliver Rider

Open access · hybridAbstract readReview
In one paragraph

Review in Heart (British Cardiac Society), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Stable electron-irradiated [1-Science advances · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Imaging Methods: Magnetic Resonance Imaging.Circulation. Cardiovascular imaging · 2023
    Review
  7. Review
  8. Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Detection of increased pyruvate dehydrogenase flux in the human heart during adenosine stress test using hyperpolarized [1-Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. HyperpolarizedNMR in biomedicine · 2021
    Review
  15. Should everyone have an MRI in heart failure?Cardiovascular diagnosis and therapy · 2020
    Article
  16. Review
  17. Metabolic Imaging in Cardio-oncology.Journal of cardiovascular translational research · 2020
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew AppsOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Justin LauDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Mark PeterzanOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Stefan NeubauerOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Damian TylerDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Oliver RiderOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
John Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

METALLOTHIONEIN AND CYTOTOXIC DRUG RESISTANCEK08CA001490 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHNSON, ROBERT R · 1990 to 1994
–
British Heart Foundation FS/10/002/28078British Heart Foundation FS/14/17/30634British Heart Foundation FS/17/18/32449British Heart Foundation RE/13/1/30181British Heart Foundation RG/11/9/28921Medical Research Council G0601490
6 · The paper itself

Abstract

Although non-invasive perfusion and viability imaging often provide the gateway to coronary revascularisation, current non-invasive imaging methods only report the surrogate markers of inducible hypoperfusion and presence or absence of myocardial scar, rather than actually visualising areas of ischaemia and/or viable myocardium. This may lead to suboptimal revascularisation decisions. Normally respiring (viable) cardiomyocytes convert pyruvate to acetyl-CoA and CO

Indexed as

Heart FailureHumansMagnetic Resonance Imaging, CineMyocardiumcardiac magnetic resonance (CMR) imagingcoronary artery disease

Identifiers

PMID29703741
PMCPMC6161668
OpenAlexW2799601527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.