Evidence map›Paper›PMID 29703583›Full record

ReviewTrends in biotechnology2018

Nanoparticle-Mediated Delivery towards Advancing Plant Genetic Engineering.

Francis J Cunningham, Natalie S Goh, Gozde S Demirer, Juliana L Matos, Markita P Landry

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

148 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Genome Editing Approaches in Flax (International journal of molecular sciences · 2026
    Review
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  8. Review
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  10. Article
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  14. Article
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  16. Single-walled carbon nanotube-mediated plasmid DNA delivery in the model monocotTurkish journal of biology = Turk biyoloji dergisi · 2026
    Article
  17. Review
  18. Review
  19. Review
  20. Article

88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francis J CunninghamDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA 94720, USA; These authors contributed equally to this work.
Natalie S GohDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA 94720, USA; These authors contributed equally to this work.
Gozde S DemirerDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA 94720, USA.
Juliana L MatosDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA; Innovative Genomics Institute (IGI), Berkeley, CA 94720, USA.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute (IGI), Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, CA 94720, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: landry@berkeley.edu.

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Genetic engineering of plants has enhanced crop productivity in the face of climate change and a growing global population by conferring desirable genetic traits to agricultural crops. Efficient genetic transformation in plants remains a challenge due to the cell wall, a barrier to exogenous biomolecule delivery. Conventional delivery methods are inefficient, damaging to tissue, or are only effective in a limited number of plant species. Nanoparticles are promising materials for biomolecule delivery, owing to their ability to traverse plant cell walls without external force and highly tunable physicochemical properties for diverse cargo conjugation and broad host range applicability. With the advent of engineered nuclease biotechnologies, we discuss the potential of nanoparticles as an optimal platform to deliver biomolecules to plants for genetic engineering.

Indexed as

Plants, Genetically ModifiedAgrobacterium tumefaciensBiolisticsCell WallCrops, AgriculturalElectroporationGene EditingGenetic EngineeringGenome, PlantGovernment RegulationHumansMicroinjectionsNanoparticlesPlant CellsTransformation, GeneticTransgenesbiomolecule deliverygene editingnanoparticleplants

Identifiers

PMID29703583
PMCPMC10461776

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.