Evidence map›Paper›PMID 29703257›Full record

ArticleBMC biology2018

InsP

Long Yang, Wenwen Gu, King-Ho Cheung, Lan Yan, Benjamin Chun-Kit Tong, Yuanying Jiang, Jun Yang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Article
  4. Review
  5. SEC5 is involved in M2 polarization of macrophagesFrontiers in cell and developmental biology · 2022
    Article
  6. Correction to: InsPBMC biology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Long YangSchool of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, China.
Wenwen GuNHFPC Key Laboratory of Reproduction Regulation, Shanghai Institute of Planned Parenthood Research, 2140 Xie Tu Road, Shanghai, 200032, China.
King-Ho CheungSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Lan YanSchool of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, China.
Benjamin Chun-Kit TongSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Yuanying JiangSchool of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, China. 13761571578@163.com.
Jun YangNHFPC Key Laboratory of Reproduction Regulation, Shanghai Institute of Planned Parenthood Research, 2140 Xie Tu Road, Shanghai, 200032, China. junyangsd@yahoo.com.
Hong Kong Baptist University · HKSecond Military Medical University · CNShanghai Institute of Planned Parenthood Research · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandida albicans (C. albicans) invasion triggers antifungal innate immunity, and the elevation of cytoplasmic Ca

resultsIn the present study, we find that during C. albicans phagocytosis in macrophages, exocyst complex component 2 (SEC5) promotes InsP

conclusionsOur data have revealed an important role of the InsP

Indexed as

AnimalsCalciumCandida albicansCytoplasmCytosolHEK293 CellsHumansImmunity, InnateInterferon Regulatory Factor-3Interferon Type IMicePhagocytosisPhagosomesVesicular Transport ProteinsCalciumExoc2 protein, mouseInterferon Regulatory Factor-3Interferon Type IVesicular Transport ProteinsAntifungal innate immune responseExocyst complex component 2 (SEC5)Inositol 1,4,5-trisphosphate receptors (InsP3R)Tank-binding kinase 1 (TBK1)

Identifiers

PMID29703257
PMCPMC5921305
OpenAlexW2800185684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.