Evidence map›Paper›PMID 29703190›Full record

ArticleRespiratory research2018

Prenatal fine particulate exposure associated with reduced childhood lung function and nasal epithelia GSTP1 hypermethylation: Sex-specific effects.

Alison G Lee, Blake Le Grand, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu, Kasey J Brennan, Sonali Bose, Maria José Rosa, Kelly J Brunst, Itai Kloog, Ander Wilson and 6 more

Open access · goldAbstract read
In one paragraph

Article in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Trial
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  4. Trial
  5. Prenatal PMRespirology (Carlton, Vic.) · 2026
    Article
  6. Early Gestational Wildfire-Related PMInternational journal of environmental research and public health · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Effect of In utero Exposure to Air Pollution on Adulthood Hospitalizations.Journal of urban health : bulletin of the New York Academy of Medicine · 2024
    Review
  15. Article
  16. Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Alison G LeeDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, 1236 Park Avenue, First Floor, New York, NY, 10029, USA. Alison.Lee@mssm.edu.
Blake Le GrandDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hsiao-Hsien Leon HsuDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Yueh-Hsiu Mathilda ChiuDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kasey J BrennanDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Sonali BoseDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, 1236 Park Avenue, First Floor, New York, NY, 10029, USA.
Maria José RosaDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kelly J BrunstDepartment of Environmental Health, University of Cincinnati College of Medicine, 160 Panzeca Way, Cincinnati, OH, USA.
Itai KloogDepartment of Geography and Environmental Development, Faculty of Humanities and Social Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Ander WilsonDepartment of Statistics, Colorado State University, Fort Collins, CO, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Wayne MorganDepartment of Pediatrics, University of Arizona, Tucson, Arizona, USA.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Robert O WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrea A BaccarelliDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USColumbia University · USHarvard University · USBen-Gurion University of the Negev · ILColorado State University · USUniversity of Arizona · USUniversity of Cincinnati Medical Center · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Gary Adamkiewicz · 1985 to 2026
$44.6M
REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
Stress, Environment, and Genetics in Urban AsthmaR01HL080674 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2005 to 2014
$7.0M
Northwestern/Nigeria Research Training Program in HIV and Malignancies (NN-HAM)D43TW009575 · FIC · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Chad J Achenbach, Jonah Musa · 2014 to 2026
$4.1M
MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISKR01ES010932 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2000 to 2004
$3.0M
Air pollution, stress and urban child developmentR01MD006086 · NIMHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2010 to 2014
$2.2M
Asthma Coalition on Community, Environment and StressU01HL072494 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2002 to 2003
$1.5M
Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stressK23HL135349 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LEE, ALISON G · 2017 to 2021
$884k
Mitochondrial Markers of Pollution, Stress, and NeurobehaviorR00ES024116 · NIEHS · UNIVERSITY OF CINCINNATI · PI BRUNST, KELLY J · 2017 to 2019
$743k
NHLBI NIH HHS K23 HL135349NHLBI NIH HHS R01 HL080674NHLBI NIH HHS U01 HL072494NHLBI NIH HHS U01 HL072494)NIEHS NIH HHS K99 ES027496NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P30ES009089NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES010932NIEHS NIH HHS T32 ES007142NIMHD NIH HHS R01 MD006086
6 · The paper itself

Abstract

backgroundIn utero exposure to particulate matter with an aerodynamic diameter of less than 2.5 μm (PM

methodsWe prospectively examined associations among prenatal PM

resultsBDLIMs identified a sensitive window for prenatal PM

conclusionsPrenatal PM

Indexed as

Sex CharacteristicsAdultAir PollutantsChildCohort StudiesDNA MethylationFemaleGlutathione S-Transferase piHumansMaleNasal MucosaParticle SizeParticulate MatterPregnancyPrenatal Exposure Delayed EffectsProspective StudiesAir PollutantsGlutathione S-Transferase piGSTP1 protein, humanParticulate Matter

Identifiers

PMID29703190
PMCPMC5923186
OpenAlexW2803945733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.