ArticleJournal of pineal research2018
Melatonin and its derivatives counteract the ultraviolet B radiation-induced damage in human and porcine skin ex vivo.
Expression of concernAbstract read
In one paragraph
Article in Journal of pineal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 62 papers.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 101 citations in OpenAlex.
- Integrated fetal testicular transcriptomic and epigenomic profiles during maternal nutrient restriction with dietary melatonin intervention.Journal of animal science · 2026Article
- Melatonin and the Skin: Current Progress and Perspectives for Human Health.The Journal of investigative dermatology · 2025Review
- Exploring melatonin's signalling pathways in the protection against age-related skin deterioration.Pharmacological reports : PR · 2025Review
- Regulation of dermal circadian pathways by a novel topical formulation.International journal of cosmetic science · 2025Article
- Lipidomic and Instrumental Evaluation of a Melatonin-Based In & Out Strategy Versus Topical Treatment in Skin Aging: A Randomized Prospective Trial.Metabolites · 2025Article
- Curcumin targets YAP1 to enhance mitochondrial function and autophagy, protecting against UVB-induced photodamage.Frontiers in immunology · 2025Article
- The Influence of Circadian Rhythms on DNA Damage Repair in Skin Photoaging.International journal of molecular sciences · 2024Review
- Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage.Biological reviews of the Cambridge Philosophical Society · 2024Review
- Ameliorative effects of topical ramelteon on imiquimod-induced psoriasiform inflammation in mice.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- The Vital Role of Melatonin and Its Metabolites in the Neuroprotection and Retardation of Brain Aging.International journal of molecular sciences · 2024Review
- Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024Review
- Ultraviolet and infrared radiation in Australia: assessing the benefits, risks, and optimal exposure guidelines.Frontiers in public health · 2024Review
- The characteristics and biological activity enhancements of melatonin encapsulations for skin care product applications.International journal of pharmaceutics: X · 2023Article
- Fisetin Inhibits UVA-Induced Expression of MMP-1 and MMP-3 through the NOX/ROS/MAPK Pathway in Human Dermal Fibroblasts and Human Epidermal Keratinocytes.International journal of molecular sciences · 2023Article
- Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma.International journal of molecular sciences · 2023Article
- Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes.Metabolites · 2023Article
- Melatonin: A Potential Regulator of DNA Methylation.Antioxidants (Basel, Switzerland) · 2023Review
- Xenopus: An in vivo model for studying skin response to ultraviolet B irradiation.Development, growth & differentiation · 2023Article
- The Melatonin-Mitochondrial Axis: Engaging the Repercussions of Ultraviolet Radiation Photoaging on the Skin's Circadian Rhythm.Antioxidants (Basel, Switzerland) · 2023Review
- Mechanism of action and promising clinical application of melatonin from a dermatological perspective.Journal of translational autoimmunity · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
- Expression of concern
Authors and funding
9 authors at 4 institutions in 3 countries.
Cezary SkobowiatFaculty of Pharmacy, Collegium Medicum, Department of Pharmacodynamics and Molecular Pharmacology, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Anna A BrożynaDepartment of Dermatology, Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Zorica JanjetovicDepartment of Dermatology, Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Saowanee JeayengFaculty of Medicine Siriraj Hospital, Department of Pharmacology, Mahidol University, Bangkok, Thailand.
Allen S W OakDepartment of Dermatology, Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Tae-Kang KimDepartment of Dermatology, Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Uraiwan PanichFaculty of Medicine Siriraj Hospital, Department of Pharmacology, Mahidol University, Bangkok, Thailand.
Russel J ReiterDepartment of Cell Systems and Anatomy, UT Health, San Antonio, TX, USA.
Andrzej T SlominskiDepartment of Dermatology, Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID http://orcid.org/0000-0001-8963-3995
University of Alabama at Birmingham · USNicolaus Copernicus University · PLSiriraj Hospital · THThe University of Texas Health Science Center at San Antonio · US
Funding
Significance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6MRole of Exogenous Melatonin in Skin BiologyR01AR056666 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2011 to 2015
$1.6MNIAMS NIH HHS R01 AR056666NIAMS NIH HHS R01 AR071189
Abstract
Melatonin and its derivatives (N
Indexed as
DNA DamageOxidative Stress8-Hydroxy-2'-DeoxyguanosineAnimalsCell LineDeoxyguanosineHumansMelatoninSkinSwineUltraviolet Rays8-Hydroxy-2'-DeoxyguanosineDeoxyguanosineMelatoninepidermismelatoninphotoprotectionskinUVB
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.