Observational studyAmerican journal of perinatology2018
Neonatal Morbidities among Moderately Preterm Infants with and without Exposure to Antenatal Corticosteroids.
Observational study in American journal of perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Perinatal management: Lessons learned from the neonatal research network.Seminars in perinatology · 2022Article
- Contributions of the NICHD neonatal research network's generic database to documenting and advancing the outcomes of extremely preterm infants.Seminars in perinatology · 2022Article
- Association of antenatal steroids with neonatal mortality and morbidity in preterm infants born to mothers with diabetes mellitus and hypertension.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Influence of Timing of Antenatal Corticosteroid Administration on Morbidity of Preterm Neonates.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveWe aimed to compare the rates of "surfactant treated respiratory disease" and other neonatal morbidities among moderately preterm (MPT) infants exposed to no, partial, or a complete course of antenatal corticosteroids (ANS). STUDY
designThis observational cohort study evaluated MPT infants (29
resultsData were available for 5,886 infants, including 676 with no exposure, 1225 with partial, and 3,985 with a complete course of ANS. Among no, partial, and complete ANS groups, respectively, there were significant differences in rates of delivery room resuscitation (4.1, 1.4, and 1.2%), surfactant-treated respiratory disease (26.5, 26.3, and 20%), and severe intracranial hemorrhage (3, 2, and 0.8%). Complete ANS course was associated with lower surfactant-treated respiratory disease, compared with partial ANS (odds ratio [OR] 0.62; 95% confidence interval [CI] 0.52-0.74), and no ANS groups (OR 0.52; 95% CI 0.41-0.66) on adjusted analysis.
conclusionIn MPT infants, ANS exposure is associated with lower delivery room resuscitation, surfactant-treated respiratory disease, and severe intracranial hemorrhage; with the lowest frequency of morbidities associated with a complete course.
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