Evidence map›Paper›PMID 29702561›Full record

ReviewInternational journal of molecular sciences2018

Intracellular Transport of Silver and Gold Nanoparticles and Biological Responses: An Update.

Elisa Panzarini, Stefania Mariano, Elisabetta Carata, Francesco Mura, Marco Rossi, Luciana Dini

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
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  12. Plant-mediated green synthesis of gold nanoparticles using an aqueous extract ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
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  19. Gold Nanoparticles Contact with Cancer Cell: A Brief Update.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisa PanzariniDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy. elisa.panzarini@unisalento.it.ORCID 0000-0003-4219-4272
Stefania MarianoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy. stefania.mariano@unisalento.it.
Elisabetta CarataDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy. elisabetta.carata@unisalento.it.
Francesco MuraDepartment of Basic and Applied Science to Engineering, Sapienza University of Rome, 00161 Rome, Italy. francesco.mura@uniroma1.it.
Marco RossiDepartment of Basic and Applied Science to Engineering, Sapienza University of Rome, 00161 Rome, Italy. marco.rossi@uniroma1.it.
Luciana DiniDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy. luciana.dini@unisalento.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicine, food, and cosmetics represent the new promising applications for silver (Ag) and gold (Au) nanoparticles (NPs). AgNPs are most commonly used in food and cosmetics; conversely, the main applications of gold NPs (AuNPs) are in the medical field. Thus, in view of the risk of accidentally or non-intended uptake of NPs deriving from the use of cosmetics, drugs, and food, the study of NPs⁻cell interactions represents a key question that puzzles researchers in both the nanomedicine and nanotoxicology fields. The response of cells starts when the NPs bind to the cell surface or when they are internalized. The amount and modality of their uptake depend on many and diverse parameters, such as NPs and cell types. Here, we discuss the state of the art of the knowledge and the uncertainties regarding the biological consequences of AgNPs and AuNPs, focusing on NPs cell uptake, location, and translocation. Finally, a section will be dedicated to the most currently available methods for qualitative and quantitative analysis of intracellular transport of metal NPs.

Indexed as

EndocytosisAnimalsBiological TransportCosmeticsFoodGoldHumansLysosomesMetal NanoparticlesModels, AnimalNanomedicineOccupational MedicineParticle SizeSilverCosmeticsGoldSilvercellular responsesfoodgold-nanoparticlesmedicinemetal-nanoparticlesoccupational exposuresilver-nanoparticlesuptake

Identifiers

PMID29702561
PMCPMC5983807

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.