Evidence map›Paper›PMID 29702490›Full record

ReviewCurrent opinion in nephrology and hypertension2018

Rationale to reduce calcium intake in adult patients with chronic kidney disease.

Sharon M Moe

Abstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  7. Nutritional Supplements and Skeletal Health.Current osteoporosis reports · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sharon M MoeDivision of Nephrology, Indiana University School of Medicine.
Indiana University · US

Funding

Resource CoreP30AR072581 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe · 2017 to 2026
$8.3M
Pathogenesis of compromised bone quality and mechanics in chronic kidney disease.R01DK110871 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ALLEN, MATTHEW R, MOE, SHARON M · 2016 to 2019
$1.8M
Bisphosphonates in the treatment of chronic kidney disease-mineral bone diseaseR01AR058005 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M · 2010 to 2014
$1.6M
Genetic risks for cardiovascular events in ESRD patients from the EVOLVE study.R01DK100306 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M · 2014 to 2016
$1.0M
The Mechanism of Uremia Induced Vascular CalcificationI01BX001471 · VA · RLR VA MEDICAL CENTER · PI MOE, SHARON M · 2012 to 2020
–
BLRD VA I01 BX001471NIAMS NIH HHS P30 AR072581NIAMS NIH HHS R01 AR058005NIDDK NIH HHS R01 DK100306NIDDK NIH HHS R01 DK110871
6 · The paper itself

Abstract

purpose of reviewCalcium is an essential ion for the maintenance of normal bone health and physiologic functions. The extracellular and intracellular levels of calcium are maintained through hormonal regulation called homeostasis. Balance, the net intake minus excretion of calcium, is maintained by hormonal regulation of intestinal absorption and fecal/urinary excretion. Homeostasis and balance are disconnected in patients with chronic kidney disease (CKD). The purpose of this review is to understand how calcium homeostasis and balance are impaired in CKD. RECENT

findingsTwo formal calcium balance studies have found that an oral intake of 800-1000 mg of calcium in adults with CKD leads to neutral calcium balance, whereas amounts greater than that lead to positive calcium balance. In patients with CKD, the main determinant of positive calcium balance is the intake and the lack of urinary calcium excretion. SUMMARY: Calcium balance is different in patients with advanced CKD compared with patients without CKD. Thus, the oral intake of calcium in the form of diet and binders should not exceed 800-1000 mg/day to achieve neutral calcium balance in adult patients with CKD stages 3b/4.

Indexed as

HomeostasisAdultCalciumCalcium, DietaryDietary SupplementsHumansRenal Insufficiency, ChronicCalciumCalcium, Dietary

Identifiers

PMID29702490
PMCPMC6454891
OpenAlexW2801260037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.