ArticleJournal of psychiatric research2018
Individual differences in corticolimbic structural profiles linked to insecure attachment and coping styles in motor functional neurological disorders.
Article in Journal of psychiatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Structural alterations in functional neurological disorder and related conditions: a software and hardware problem?NeuroImage. Clinical · 2019Pooled it
- Attachment State of Mind and complex traumatization in patients with Functional Motor Disorder (Motor Conversion Disorder).Brain, behavior, & immunity - health · 2024Article
- Long COVID Is Not a Functional Neurologic Disorder.Journal of personalized medicine · 2024Review
- Psychological Factors Associated with Functional Tic-like Behaviours during the COVID-19 Pandemic.Research on child and adolescent psychopathology · 2024Article
- Understanding Functional Neurological Disorder: Recent Insights and Diagnostic Challenges.International journal of molecular sciences · 2024Review
- The key role of depression and supramarginal gyrus in frailty: a cross-sectional study.Frontiers in aging neuroscience · 2023Article
- Homologous recombination repair gene mutations as a predictive biomarker for immunotherapy in patients with advanced melanoma.Frontiers in immunology · 2022Article
- Reduced limbic microstructural integrity in functional neurological disorder.Psychological medicine · 2021Article
- Neuroimaging Biomarkers Predicting the Efficacy of Multimodal Rehabilitative Intervention in the Alzheimer's Dementia Continuum Pathology.Frontiers in aging neuroscience · 2021Article
- Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda.NeuroImage. Clinical · 2021Review
- Sex Effects on Coping, Dissociation, and PTSD in Patients With Non-epileptic Seizures.Current psychiatry reports · 2020Review
- Individual differences in social network size linked to nucleus accumbens and hippocampal volumes in functional neurological disorder: A pilot study.Journal of affective disorders · 2019Article
- Emotional processing in functional neurological disorder: a review, biopsychosocial model and research agenda.Journal of neurology, neurosurgery, and psychiatry · 2019Review
- Neuroimaging in Functional Movement Disorders.Current neurology and neuroscience reports · 2019Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundInsecure attachment and maladaptive coping are important predisposing vulnerabilities for Functional Neurological Disorders (FND)/Conversion Disorder, yet no prior structural neuroimaging studies have investigated biomarkers associated with these risk factors in FND populations. This magnetic resonance imaging study examined cortical thickness and subcortical volumes associated with self-reported attachment and coping styles in patients with FND. We hypothesized that insecure attachment and maladaptive coping would relate to limbic-paralimbic structural alterations.
methodsFreeSurfer cortical thickness and subcortical volumetric analyses were performed in 26 patients with motor FND (21 women; 5 men) and 27 healthy controls (22 women; 5 men). For between-group comparisons, patients with FND were stratified by Relationship Scales Questionnaire, Ways of Coping Scale-Revised, and Connor-Davidson Resilience Scale scores. Within-group analyses were also performed in patients with FND. All analyses were performed in the complete cohort and separately in women only to evaluate for gender-specific effects. Cortical thickness analyses were whole-brain corrected at the cluster-wise level; subcortical analyses were Bonferroni corrected.
resultsIn women with FND, dismissing attachment correlated with reduced left parahippocampal cortical thickness. Confrontive coping was associated with reduced right hippocampal volume, while accepting responsibility positively correlated with right precentral gyrus cortical thickness. These findings held adjusting for anti-depressant use. All FND-related findings were within the normal range when compared to healthy women.
conclusionThese observations connect individual-differences in limbic-paralimbic and premotor structures to attachment and coping styles in FND. The relationship between parahippocampal thickness and dismissing attachment may indicate aberrant social-emotional and contextual appraisal in women with FND.
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