ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2018
Advances in Management of Esophageal Motility Disorders.
Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Short Versus Standard Peroral Endoscopic Myotomy for Esophageal Achalasia: A Meta-Analysis of Randomized Controlled Trials.Digestive diseases and sciences · 2025Pooled it
- Interpretable Machine Learning Enables Preoperative Physiologic Risk Stratification for Dysphagia After Anti-Reflux Surgery.Research square · 2026Article
- Vitamin D3 ameliorates inflammation and autonomic dysfunction in a rat model of reflux esophagitis via modulation of IL-6 and TNF-α.Scientific reports · 2025Article
- Peroral endoscopic myotomy: a Danish single center 10-year follow-up study.Surgical endoscopy · 2025Article
- The Critical Importance of Preoperative Esophageal Testing in Bariatric Surgery.Obesity surgery · 2025Article
- Evaluation of postoperative esophagram following peroral endoscopic myotomy (POEM).Surgical endoscopy · 2024Article
- Association of esophageal motility disorder symptoms with Chicago classification versions 3.0 and 4.0 using high-resolution esophageal manometry: A single-center experience from Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024Article
- Diagnostic methods to measure spastic segment and guide tailored myotomy length in type 3 achalasia.Neurogastroenterology and motility · 2023Article
- Article
- Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research.Pharmaceutics · 2022Review
- A Comparative Assessment of the Diagnosis of Swallowing Impairment and Gastroesophageal Reflux in Canines and Humans.Frontiers in veterinary science · 2022Review
- Evaluating the impact of an enhanced triage process on the performance and diagnostic yield of oesophageal physiology studies post COVID-19.BMJ open gastroenterology · 2021Article
- Predictors of Abnormal Functional Luminal Impedance Planimetry Findings in Non-mechanical Esophagogastric Junction Outflow Obstruction.Digestive diseases and sciences · 2021Article
- Discordance between high-resolution manometry, esophagoscopy and contrast esophagogram in determining landmarks for per-oral endoscopic myotomy in spastic esophageal disorders: a word of caution.Surgical endoscopy · 2021Article
- Short versus standard esophageal myotomy in achalasia patients: a systematic review and meta-analysis of comparative studies.Endoscopy international open · 2021Article
- Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows.Scientific reports · 2021Observational
- Peroral Endoscopic Myotomy for Esophageal Achalasia in Portugal: Outcomes of the First Prospective Series.GE Portuguese journal of gastroenterology · 2021Article
- [Pharmacological Treatments of Esophageal Dysphagia].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- Long-term outcomes of per-oral endoscopic myotomy compared to laparoscopic Heller myotomy for achalasia: a single-center experience.Surgical endoscopy · 2021Article
- High Resolution Manometry Guidance During Laparoscopic Fundoplication in Pediatric Surgically "Fragile" Patients: Preliminary Report.Children (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The widespread adoption of high-resolution manometry (HRM) has led to a restructuring in the classification of esophageal motility disorder classification summarized in the Chicago Classification, currently in version 3.0. It has become apparent that the cardinal feature of achalasia, impaired lower esophageal sphincter relaxation, can occur in several disease phenotypes: without peristalsis, with premature (spastic) distal esophageal contractions, with panesophageal pressurization, or even with preserved peristalsis. Furthermore, despite these advances in diagnostics, no single manometric pattern is perfectly sensitive or specific for idiopathic achalasia and complimentary assessments with provocative maneuvers during HRM or interrogating the esophagogastric junction with the functional luminal imaging probe during endoscopy can be useful in clarifying equivocal or inexplicable HRM findings. Using these tools, we have come to conceptualize esophageal motility disorders as characterized by obstructive physiology at the esophagogastric junction, smooth muscle esophagus, or both. Recognizing obstructive physiology as a primary target of therapy has become particularly relevant with the development of a minimally invasive technique for performing a calibrated myotomy of the esophageal circular muscle, the POEM procedure. Now and going forward, optimal management is to render treatment in a phenotype-specific manner: e.g. POEM calibrated to patient-specific physiology for spastic achalasia and spastic disorders of the smooth muscle esophagus, more conservative strategies (pneumatic dilation) for the disorders limited to the sphincter.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.