ArticleThe Permanente journal2018
Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework.
Article in The Permanente journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Perspective: Food Environment, Climate Change, Inflammation, Diet, and Health.Advances in nutrition (Bethesda, Md.) · 2025Review
- Resilience following childhood adversity: The need for a heuristic multilevel dynamic framework.Neuroscience applied · 2024Article
- Resilience in Older People: A Concept Analysis.Healthcare (Basel, Switzerland) · 2023Article
- Association Between Adverse Childhood Experiences, Resilience and Mental Health in a Hispanic Community.Journal of child & adolescent trauma · 2022Article
- Plant-based dietary intake moderates adverse childhood experiences association with early mortality in an older Adventist cohort.Journal of psychosomatic research · 2021Observational
- Vegetarian diets, circulating miRNA expression and healthspan in subjects living in the Blue Zone.Precision clinical medicine · 2020Article
- [Action-related resilience in people with longevity-sociological approach].Zeitschrift fur Gerontologie und Geriatrie · 2020Article
- Exploring health-related quality of life of Spanish domestic adult adoptees: sociodemographic characteristics, chronic medical conditions, and gender differences.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextResearch has linked adverse childhood experiences (ACEs) with chronic disease in adults and diminished life span. Adverse biological embedding of ACEs potentially occurs through inflammatory mechanisms; inflammatory marker alterations are identified as candidate biomarkers for mediating health consequences. Lifestyle practices of residents of California's Loma Linda Blue Zone, one of five worldwide longevity hotspots, may provide insight into inflammation remediation and chronic disease prevention. Little research has been done on centenarians' early-life experiences or on ACEs in a longevity community.
objectiveTo interview centenarians and seniors in this region regarding their childhood experiences to inform chronic disease prevention frameworks.
designQualitative study of Loma Linda Blue Zone community members. Childhood exposures and practices were assessed using focus groups and semistructured key informant interviews, with open-ended questions on general hardships and ACEs and supplemented with lifestyle and resiliency factor questions. Data were audiorecorded and transcribed. Integrative grounded theory methods guided coding and theming.
main outcome measuresExposure to ACEs and practice of resiliency factors.
resultsParticipants (7 centenarians and 29 seniors) reported exposure to multiple ACEs (domains: Economic deprivation, family dysfunction, and community violence). Community members reported practicing resiliency factors, each with anti-inflammatory properties suggesting mitigation of ACE-related toxic stress.
conclusionThis is one of the first studies of its kind to identify a community of resilient members despite their tremendous burden of ACEs. Embedding the identified resiliency factors into chronic disease prevention frameworks has potential for mitigating systemic inflammation, alleviating chronic disease burden, and promoting a culture of health.
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