Evidence map›Paper›PMID 29701801›Full record

ArticleAmerican journal of hypertension2018

Determinants of Uncontrolled Hypertension in Rural Communities in South Asia-Bangladesh, Pakistan, and Sri Lanka.

Tazeen H Jafar, Mihir Gandhi, Imtiaz Jehan, Aliya Naheed, H Asita de Silva, Hunaina Shahab, Dewan Alam, Nathasha Luke, Ching Wee Lim, COBRA-BPS Study Group

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in American journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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  9. Beyond medication: factors contributing to uncontrolled hypertension from the 2023 Indonesian health survey.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
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  11. Global trends in hypertension prevalence, awareness, treatment, and control.Current opinion in nephrology and hypertension · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 7 countries.

Tazeen H JafarProgram in Health Services & Systems Research, Duke-NUS Medical School, Singapore.
Mihir GandhiBiostatistics, Singapore Clinical Research Institute, Singapore.
Imtiaz JehanDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Aliya NaheedInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
H Asita de SilvaClinical Trials Unit, Department of Pharmacology, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Hunaina ShahabDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Dewan AlamInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Nathasha LukeClinical Trials Unit, Department of Pharmacology, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Ching Wee LimProgram in Health Services & Systems Research, Duke-NUS Medical School, Singapore.
COBRA-BPS Study Group
Aga Khan University · PKDuke-NUS Medical School · SGInternational Centre for Diarrhoeal Disease Research · BDUniversity of Kelaniya · LKDuke Institute for Health Innovation · US

Funding

Medical Research Council MR/N006178/1Wellcome Trust
6 · The paper itself

Abstract

backgroundUncontrolled blood pressure (BP) is a leading risk factor for death and disability in South Asia. We aimed to determine the cross-country variation, and the factors associated with uncontrolled BP among adults treated for hypertension in rural South Asia.

methodsWe enrolled 1,718 individuals aged ≥40 years treated for hypertension in a cross-sectional study from rural communities in Bangladesh, Pakistan, and Sri Lanka. Multivariable logistic regression model was used to determine the factors associated with uncontrolled BP (systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg).

resultsAmong hypertensive individuals, 58.0% (95% confidence interval (CI) 55.7, 60.4) had uncontrolled BP: 52.8% (49.0, 56.6) in Bangladesh, 70.6% (65.7, 75.1) in Pakistan, and 56.5% (52.7, 60.1) in Sri Lanka. The odds (odds ratio (95% CI)) of uncontrolled BP were significantly higher in individuals with lower wealth index (1.17 (1.02, 1.35)); single vs. married (1.46 (1.10, 1.93)); higher log urine albumin-to-creatinine ratio (1.41 (1.24, 1.60)); lower estimated glomerular filtration rate (1.23 (1.01, 1.49)); low vs. high adherence to antihypertensive medication (1.50 (1.16, 1.94)); and Pakistan (2.91 (1.60, 5.28)) vs. Sri Lanka. However, the odds were lower in those with vs. without self-reported kidney disease (0.51 (0.28, 0.91)); and receiving vs. not receiving statins (0.62 (0.44, 0.87)).

conclusionsThe majority of individuals with treated hypertension have uncontrolled BP in rural Bangladesh, Pakistan, and Sri Lanka with significant disparities among and within countries. Urgent public health efforts are needed to improve access and adherence to antihypertensive medications in disadvantaged populations in rural South Asia.

Indexed as

Rural HealthAdultAgedAntihypertensive AgentsBangladeshBlood PressureComorbidityCross-Sectional StudiesFemaleHealthcare DisparitiesHealth Care SurveysHumansHypertensionMaleMedication AdherenceMiddle AgedAntihypertensive Agents

Identifiers

PMID29701801
PMCPMC6188532
OpenAlexW2799551310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.