ArticleJournal of clinical laboratory analysis2018
Serum carbohydrate antigen 153 and renal function in patients with type 2 diabetes mellitus.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Changes in serum tumor markers in type 2 diabetes mellitus with microalbuminuria.Frontiers in endocrinology · 2023Article
- Changes of Tumor Markers in Patients with Breast Cancer during Postoperative Adjuvant Chemotherapy.Disease markers · 2022Article
- The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients.Journal of clinical laboratory analysis · 2020Observational
- Serum carbohydrate antigen 153 and renal function in patients with type 2 diabetes mellitus.Journal of clinical laboratory analysis · 2018Article
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4 authors.
Funding
Abstract
objectiveThe aim of our study was to investigate the correlation between serum carbohydrate antigen 153 (CA153) and renal function in patients with type 2 diabetes mellitus (T2DM).
methodsA total of 184 patients with T2DM were included, and renal function was assessed by the modification of diet in renal disease (MDRD) formula adjusted coefficient of the Chinese people.
resultsSerum CA153 concentrations were positively correlated with blood glucose (BG) and glycated hemoglobin (HbA1c) (r = .204, P = .005; r = .165, P = .025) in patients with T2DM. There was a negative correlation between serum CA153 and estimated glomerular filtration rate (GFR) (r = -.229, P = .002) in whole patients with T2DM; similarly, the correlations were observed in both women and men (r = -.228, P = .028 for women, r = -.231, P = .028 for men). Multiple linear regression analysis suggested that serum CA153 was still significantly correlated with estimated GFR (beta = -0.286, P < .001).
conclusionsSerum CA153 is negatively correlated with estimated GFR in patients with T2DM, and serum CA153 may be a potentially useful clinical biomarker to assess renal function in the study population.
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