ReviewBritish journal of clinical pharmacology2018
Cannabis, from plant to pill.
Review in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04280289 (CBD Cannabis Extract), which is not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CBD Cannabis Extract: Pharmacokinetic Studies
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Cannabidiol on Appetite and Body Weight: A Systematic Review.Clinical drug investigation · 2022Pooled it
- The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: A randomised controlled trial.British journal of clinical pharmacology · 2020Trial
- Development and Characterization of a High-CBD Cannabis Extract Nanoemulsion for Oral Mucosal Delivery.International journal of molecular sciences · 2025Article
- How to ESCAPE from Pain? An Observational Study on Improving Pain and Quality of Life with the CannamedicalAdvances in therapy · 2025Observational
- Maternal ingestion of cannabidiol (CBD) in mice leads to sex-dependent changes in memory, anxiety, and metabolism in the adult offspring, and causes a decrease in survival to weaning age.Pharmacology, biochemistry, and behavior · 2025Article
- Article
- Comprehensive analysis of chemical and enantiomeric stability of terpenes in Cannabis sativa L. flowers.Phytochemical analysis : PCA · 2025Article
- Treatment Strategies for Painful Pelvic Floor Conditions: A Focus on the Potential Benefits of Cannabidiol.Biomolecules · 2024Review
- In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities.Toxicology reports · 2024Review
- The Elusive Truth of Cannabinoids for Rheumatic Pain.Current rheumatology reports · 2024Review
- Optimizing cannabis cultivation: an efficient in vitro system for flowering induction.Plant methods · 2024Article
- Comprehensive Insight into Cutaneous Application of Hemp.Pharmaceutics · 2024Review
- Phytocannabinoids: Exploring Pharmacological Profiles and Their Impact on Therapeutical Use.International journal of molecular sciences · 2024Review
- Identification and expression analysis ofHeliyon · 2024Article
- Integrated Management of Pathogens and Microbes inPlants (Basel, Switzerland) · 2024Review
- Bioengineering of the Marine DiatomInternational journal of molecular sciences · 2023Article
- The Role of Hemp (Foods (Basel, Switzerland) · 2023Review
- Article
- Identification of circular RNAs of Cannabis sativa L. potentially involved in the biosynthesis of cannabinoids.Planta · 2023Article
- Cannabis in Adolescence: Lasting Cognitive Alterations and Underlying Mechanisms.Cannabis and cannabinoid research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The therapeutic application of cannabis is attracting substantial public and clinical interest. The cannabis plant has been described as a veritable 'treasure trove', producing more than 100 different cannabinoids, although the focus to date has been on the psychoactive molecule delta-9-tetraydrocannabinol (THC) and cannabidiol (CBD). Other numerous secondary metabolites of cannabis, the terpenes, some of which share the common intermediary geranyl diphosphate (GPP) with the cannabinoids, are hypothesized to contribute synergistically to their therapeutic benefits, an attribute that has been described as the 'entourage effect'. The effective delivery of such a complex multicomponent pharmaceutical relies upon the stable genetic background and standardized growth of the plant material, particularly if the raw botanical product in the form of the dried pistillate inflorescence (flos) is the source. Following supercritical CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.