Evidence map›Paper›PMID 29701221›Full record

ArticleChemical communications (Cambridge, England)2018

Cysteine-activated hydrogen sulfide (H

Yu Zhao, Andrea K Steiger, Michael D Pluth

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  3. Article
  4. Enzyme-Triggered Chemodynamic Therapy via a Peptide-HAngewandte Chemie (International ed. in English) · 2023
    Article
  5. Article
  6. Article
  7. The Journal of organic chemistry · 2021
    Article
  8. Review
  9. Use of Dithiasuccinoyl-Caged Amines Enables COS/HChemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  10. Activatable Small-Molecule Hydrogen Sulfide Donors.Antioxidants & redox signaling · 2020
    Review
  11. HMethods in enzymology · 2020
    Article
  12. Development of Acid-Mediated HThe Journal of organic chemistry · 2019
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Fluorogenic hydrogen sulfide (HChemical science · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Yu ZhaoDepartment of Chemistry and Biochemistry, Institute of Molecular Biology, Materials Science Institute, University of Oregon, Eugene, OR 97403, USA. pluth@uoregon.edu.
Andrea K Steiger
Michael D Pluth
University of Oregon · US

Funding

Supplement to: Chemical Tools for Delivery and Detection of Biological Hydrogen SulfideR01GM113030 · NIGMS · UNIVERSITY OF OREGON · PI PLUTH, MICHAEL · 2015 to 2024
$2.8M
NIGMS NIH HHS R01 GM113030
6 · The paper itself

Abstract

Hydrogen sulfide (H2S) is an important biomolecule, and controllable H2S donors are needed to investigate H2S biological functions. Here we utilize cysteine-mediated addition/cyclization chemistry to unmask an acrylate-functionalized thiocarbamate and release carbonyl sulfide (COS), which is quickly converted to H2S by carbonic anhydrase (CA).

Identifiers

PMID29701221
PMCPMC5965689
OpenAlexW2802923824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.