Evidence map›Paper›PMID 29700996›Full record

ArticlePediatric obesity2018

Exposure to Bisphenol A and phthalates metabolites in the third trimester of pregnancy and BMI trajectories.

T C Yang, K E Peterson, J D Meeker, B N Sánchez, Z Zhang, A Cantoral, M Solano, M M Tellez-Rojo

Abstract read
In one paragraph

Article in Pediatric obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

T C YangDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, USA.ORCID 0000-0003-4549-7850
K E PetersonDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, USA.ORCID 0000-0003-0471-1427
J D MeekerDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, USA.
B N SánchezDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, USA.
Z ZhangDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, USA.
A CantoralCentro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
M SolanoCentro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
M M Tellez-RojoCentro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.

Funding

University of Michigan ERC-supplement (TRT)T42OH008455 · OH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NEITZEL, RICHARD L · 2005 to 2025
$32.3M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AMY J SCHULZ · 2011 to 2026
$21.3M
Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PADMANABHAN, VASANTHA, PETERSON, KAREN EILEEN · 2013 to 2018
$3.9M
Project 1: Prenatal Lead Exposure, Early Childhood Growth, and Sexual MaturationP20ES018171 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETERSON, KAREN EILEEN · 2010 to 2012
$584k
EPA RD83480019EPA RD83543601NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P20 ES018171NIEHS NIH HHS P30 ES017885NIOSH CDC HHS T42 OH008455
6 · The paper itself

Abstract

backgroundBisphenol A (BPA) and phthalates metabolites are linked to a variety of adverse health consequences but studies have not explored their association with growth trajectories.

objectiveExplore body mass index (BMI) trajectories for tertile exposures to BPA and phthalates metabolites in the third trimester of pregnancy.

methodsWe constructed BMI (kg/m

resultsHighest predicted BMI trajectories for female children were observed for third tertile exposure to the phthalate metabolite mono(2-ethyl-5-carboxypentyl) phthalate. In male children, first tertile exposure to mono-isobutyl phthalate and monobenzyl phthalate and second tertile exposure to mono(2-ethylhexyl) phthalate and mono(2-ethyl-5-hydroxyhexyl) phthalate predicted the highest BMI trajectory by adolescence. There was no relationshsip between BPA and child growth trajectory.

conclusionsThese results suggest sex-specific differences in BMI trajectories by levels of metabolite exposure. Additional studies are needed to consider growth through adolescence in assessing the association of pregnancy exposures on child's BMI.

Indexed as

Body Mass IndexAdolescentBenzhydryl CompoundsBisphenol A CompoundsChildChild, PreschoolEnvironmental ExposureFemaleFollow-Up StudiesHumansInfantInfant, NewbornMaleMexicoPhenolsPhthalic AcidsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenolsphthalic acidPhthalic AcidsBMIBPAgrowth trajectoryphthalates

Identifiers

PMID29700996
PMCPMC6988102

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.