Evidence map›Paper›PMID 29700322›Full record

ArticleScientific reports2018

Phenotypic variability between Social Dominance Ranks in laboratory mice.

Justin A Varholick, Jeremy D Bailoo, Rupert Palme, Hanno Würbel

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  6. Acetylcholine muscarinic M1 receptors in the rodent prefrontal cortex modulate cognitive abilities to establish social hierarchy.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Justin A VarholickDivision of Animal Welfare, Veterinary Public Health Institute, University of Bern, Bern, Switzerland. justin.varholick@vetsuisse.unibe.ch.
Jeremy D BailooDivision of Animal Welfare, Veterinary Public Health Institute, University of Bern, Bern, Switzerland.ORCID 0000-0002-3767-2922
Rupert PalmeDepartment of Biomedical Sciences, University of Veterinary Medicine, Vienna, Austria.ORCID 0000-0001-9466-3662
Hanno WürbelDivision of Animal Welfare, Veterinary Public Health Institute, University of Bern, Bern, Switzerland.ORCID 0000-0002-2934-3010
University of Bern · CHUniversity of Veterinary Medicine Vienna · AT

Funding

European Research Council 322576
6 · The paper itself

Abstract

The laboratory mouse is the most prevalent animal used in experimental procedures in the biomedical and behavioural sciences. Yet, many scientists fail to consider the animals' social context. Within a cage, mice may differ in their behaviour and physiology depending on their dominance relationships. Therefore, dominance relationships may be a confounding factor in animal experiments. The current study housed male and female C57BL/6ByJ mice in same-sex groups of 5 in standard laboratory conditions and investigated whether dominance hierarchies were present and stable across three weeks, and whether mice of different dominance ranks varied consistently in behaviour and physiology. We found that dominance ranks of most mice changed with time, but were most stable between the 2

Indexed as

Behavior, AnimalBiological Variation, PopulationPhenotypeSocial DominanceAnimalsBody Mass IndexFemaleGlucocorticoidsMaleMaze LearningMiceGlucocorticoids

Identifiers

PMID29700322
PMCPMC5920077
OpenAlexW2801036063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.