Evidence map›Paper›PMID 29700212›Full record

ArticleBioscience reports2018

Neonatal maternal deprivation impairs localized

Faraz Ahmad, Mohammad Salahuddin, Khaldoon Alsamman, Hatem K Herzallah, Sultan T Al-Otaibi

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Isolated Mitochondrial Preparations andCurrent neuropharmacology · 2023
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Faraz AhmadDepartment of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia famuslim@iau.edu.sa.
Mohammad SalahuddinAnimal House Department, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Khaldoon AlsammanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
Hatem K HerzallahDepartment of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Sultan T Al-OtaibiDepartment of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Imam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal neuropsychiatric stress induces alterations in neurodevelopment that can lead to irreversible damage to neuronal physiology, and social, behavioral, and cognitive skills. In addition, this culminates to an elevated vulnerability to stress and anxiety later in life. Developmental deficits in hippocampal synaptic function and plasticity are among the primary contributors of detrimental alterations in brain function induced by early-life stress. However, the underlying molecular mechanisms are not completely understood. Localized protein translation, occurring at the synapse and triggered by neuronal activity, is critical for synapse function, maintenance, and plasticity. We used a rodent model of chronic maternal deprivation to characterize the effects of early-life neuropsychiatric stress on localized

Indexed as

Maternal DeprivationProtein BiosynthesisAnimalsDisks Large Homolog 4 ProteinFemaleHippocampusMaleMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Nerve Tissue ProteinsNeuronal PlasticityNeuronsPhosphorylationPotassiumPrimary Cell CultureProtein Synthesis InhibitorsDisks Large Homolog 4 ProteinDlg4 protein, ratMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Nerve Tissue ProteinsPotassiumProtein Synthesis InhibitorsProto-Oncogene Proteins c-aktPuromycinAktearly-life stressERK1/2maternal separationneuropsychiatric stresspuromycin

Identifiers

PMID29700212
PMCPMC5997792
OpenAlexW2802481268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.