Evidence map›Paper›PMID 29700172›Full record

ArticleHaematologica2018

The early expansion of anergic NKG2A

Alessandra Roberto, Clara Di Vito, Elisa Zaghi, Emilia Maria Cristina Mazza, Arianna Capucetti, Michela Calvi, Paolo Tentorio, Veronica Zanon, Barbara Sarina, Jacopo Mariotti and 10 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. Article
  3. PD-1Journal of experimental & clinical cancer research : CR · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Harnessing Immune Response in Acute Myeloid Leukemia.Journal of clinical medicine · 2023
    Review
  12. Article
  13. Persistence of KIRFrontiers in immunology · 2023
    Article
  14. Review
  15. Article
  16. Review
  17. Abnormality in the NK-cell population is prolonged in severe COVID-19 patients.The Journal of allergy and clinical immunology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Alessandra RobertoLaboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Clara Di VitoUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Elisa ZaghiUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Emilia Maria Cristina MazzaLaboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Arianna CapucettiUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Michela CalviUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Paolo TentorioUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Veronica ZanonLaboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Barbara SarinaBone Marrow Transplant Unit, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Jacopo MariottiBone Marrow Transplant Unit, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Stefania BramantiBone Marrow Transplant Unit, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Elena TenediniDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Enrico TagliaficoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Silvio BicciatoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Armando SantoroBone Marrow Transplant Unit, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Mario RoedererImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
Emanuela MarcenaroDipartimento di Medicina Sperimentale (DI.ME.S.) and Centro di Eccellenza per le Ricerche Biomediche (CEBR) Università degli Studi di Genova, Italy.
Luca CastagnaBone Marrow Transplant Unit, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
Enrico LugliLaboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy domenico.mavilio@unimi.it enrico.lugli@humanitasresearch.it.
Domenico MavilioUnit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy domenico.mavilio@unimi.it enrico.lugli@humanitasresearch.it.
Humanitas University · ITUniversity of Modena and Reggio Emilia · ITUniversity of Genoa · IT

Funding

Flow Cytometry CoreZICAI005101 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2025
$25.7M
Functional And Phenotypic Characterization Of T Cells In ManZIAAI005021 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2022
$14.4M
Development Of Flow Cytometric Technologies For Immune AssaysZIAAI005020 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2019
$9.6M
6 · The paper itself

Abstract

Natural killer cells are the first lymphocyte population to reconstitute early after non-myeloablative and T cell-replete haploidentical hematopoietic stem cell transplantation with post-transplant infusion of cyclophosphamide. The study herein characterizes the transient and predominant expansion starting from the second week following haploidentical hematopoietic stem cell transplantation of a donor-derived unconventional subset of NKp46

Indexed as

Clonal AnergyCD56 AntigenCell ProliferationCells, CulturedGPI-Linked ProteinsHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansImmunotherapyKiller Cells, NaturalLymphocyte SubsetsNK Cell Lectin-Like Receptor Subfamily CNK Cell Lectin-Like Receptor Subfamily KReceptors, IgGTransplantation ConditioningTransplantation, HaploidenticalCD56 AntigenFCGR3B protein, humanGPI-Linked ProteinsKLRC1 protein, humanNCAM1 protein, humanNK Cell Lectin-Like Receptor Subfamily CNK Cell Lectin-Like Receptor Subfamily KReceptors, IgG

Identifiers

PMID29700172
PMCPMC6068034
OpenAlexW2801453085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.