Evidence map›Paper›PMID 29700102›Full record

ArticleThe European respiratory journal2018

Igor L Chernyavsky, Richard J Russell, Ruth M Saunders, Gavin E Morris, Rachid Berair, Amisha Singapuri, Latifa Chachi, Adel H Mansur, Peter H Howarth, Patrick Dennison and 6 more

Open access · hybridAbstract read
In one paragraph

Article in The European respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Cytokine-targeted therapies for asthma and COPD.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  8. Review
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Personalized medicine for patients with COPD: where are we?International journal of chronic obstructive pulmonary disease · 2019
    Review
  18. Review
  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Igor L ChernyavskySchool of Mathematics, University of Manchester, Manchester, UK.ORCID 0000-0003-0284-9318
Richard J RussellDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Ruth M SaundersDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Gavin E MorrisDept of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Rachid BerairDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Amisha SingapuriDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Latifa ChachiDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Adel H MansurHeart of England NHS Trust, Birmingham, UK.
Peter H HowarthClinical and Experimental Sciences, University of Southampton, Southampton NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Trust, Southampton, UK.
Patrick DennisonClinical and Experimental Sciences, University of Southampton, Southampton NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Trust, Southampton, UK.
Rekha ChaudhuriGartnavel General Hospital, Glasgow, UK.
Stephen BicknellGartnavel General Hospital, Glasgow, UK.
Felicity R A J RoseCentre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.
Salman SiddiquiDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Bindi S BrookSchool of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Christopher E BrightlingDept of Infection, Immunity and Inflammation, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
University of Leicester · GBGartnavel General Hospital · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Nottingham · GBHeart of England NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

Medical Research Council MR/M004643/1Medical Research Council MR/N011538/1Wellcome TrustWellcome Trust WT082265
6 · The paper itself

Abstract

Bronchial thermoplasty is a treatment for asthma. It is currently unclear whether its histopathological impact is sufficiently explained by the proportion of airway wall that is exposed to temperatures necessary to affect cell survival.Airway smooth muscle and bronchial epithelial cells were exposed to media (37-70°C) for 10 s to mimic thermoplasty.

Indexed as

Models, BiologicalAdultAgedAirway RemodelingApoptosisAsthmaBronchial ThermoplastyBronchoscopyComputer SimulationEpithelial CellsFemaleHumansMaleMiddle AgedMuscle, Smooth

Identifiers

PMID29700102
PMCPMC6003767
OpenAlexW2795665222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.