Evidence map›Paper›PMID 29699876›Full record

ArticleEBioMedicine2018

Therapeutic Injury and Tumor Regrowth: Tumor Resection and Radiation Establish the Recurrent Glioblastoma Microenvironment.

Daniel J Silver, Justin D Lathia

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Combinatorial treatment of glioblastoma with temozolomide (TMZ) plus 5-ethynyl-2'-deoxyuridine (EdU).Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Daniel J SilverCleveland Clinic Foundation, Lerner Research Institute, Cleveland, OH 44195, United States; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, United States. Electronic address: silverd2@ccf.org.
Justin D LathiaCleveland Clinic Foundation, Lerner Research Institute, Cleveland, OH 44195, United States; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, United States.

Funding

RESEARCH ONCOLOGY TRAINING GRANTT32CA059366 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI JACKSON, MARK W. · 1993 to 2025
$5.5M
Novel adhesion mechanisms in glioblastoma stem cellsR01NS083629 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI LATHIA, JUSTIN D. · 2013 to 2017
$1.7M
Connexins and glioblastoma progressionR01NS089641 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI LATHIA, JUSTIN D. · 2015 to 2019
$1.7M
Cell-cell communication in CSC self renewal and breast cancer progressionR21CA191263 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI LATHIA, JUSTIN D., REIZES, OFER · 2015 to 2016
$379k
Microenvironmental modulation as a result of glioma therapyK99CA157948 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI LATHIA, JUSTIN D. · 2011 to 2011
$99k
Serotonin drives cancer stem cell maintenance and glioblastoma progressionF32CA213727 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI SILVER, DANIEL J · 2017 to 2018
$94k
NCI NIH HHS F32 CA213727NCI NIH HHS K99 CA157948NCI NIH HHS R21 CA191263NCI NIH HHS T32 CA059366NINDS NIH HHS R01 NS083629NINDS NIH HHS R01 NS089641
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGlioblastomaOligodendrocyte Precursor CellsHumansMacrophagesMicrogliaNeoplasm Recurrence, LocalNeoplastic Stem CellsTumor Microenvironment

Identifiers

PMID29699876
PMCPMC6014582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.