Evidence map›Paper›PMID 29699864›Full record

ArticleTrends in molecular medicine2018

Adult Human Hippocampal Neurogenesis: Controversy and Evidence.

Hyunah Lee, Sandrine Thuret

Open access · greenAbstract readComment
PubMed Publisher
In one paragraph

Article in Trends in molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
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  7. Article
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  10. Persistence of FoxJ1Cellular and molecular life sciences : CMLS · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
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  18. Review
  19. Telomere length and human hippocampal neurogenesis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  20. Neurobiological effects of phospholipidsNeurobiology of stress · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hyunah LeeKing's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, London, UK.
Sandrine ThuretKing's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, London, UK. Electronic address: sandrine.1.thuret@kcl.ac.uk.
King's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hippocampus has been described as one of the few sites in the mammalian brain capable of generating new cells continuously throughout life. Two recent studies that report contradicting findings on adult human hippocampal neurogenesis, however, reminds us of the caveats and challenges of studying this phenomenon in postmortem tissues.

Indexed as

HippocampusNeurogenesisAdultAnimalsChildHumansadult neurogenesishippocampus

Identifiers

PMID29699864
OpenAlexW2802690582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.