SynthesisBMC pediatrics2018
Effect of childhood BMI on asthma: a systematic review and meta-analysis of case-control studies.
Synthesis in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 72 citations in OpenAlex.
- Maternal Folic Acid Supplementation, Perinatal Factors, and Pre-Adolescent Asthma: Findings from the Healthy Growth Study.Nutrients · 2025Article
- Association between BMI and asthma in adults over 45 years of age: analysis of Global Burden of Disease 2021, China Health and Retirement Longitudinal Study, and National Health and Nutrition Examination Survey data.EClinicalMedicine · 2025Article
- Socio-demographic environmental and clinical factors influencing asthma control in community pharmacies of Lahore Pakistan.Scientific reports · 2025Observational
- Article
- Conceptualizing bias in EHR data: A case study in performance disparities by demographic subgroups for a pediatric obesity incidence classifier.PLOS digital health · 2024Article
- Evaluation of Healthy Eating Index and Children's Diet Inflammatory Index according to asthma severity group.BMC pediatrics · 2024Article
- Not Only Metabolic Complications of Childhood Obesity.Nutrients · 2024Review
- Article
- Prediction of Postnatal Growth Failure in Very Low Birth Weight Infants Using a Machine Learning Model.Diagnostics (Basel, Switzerland) · 2023Article
- Metabolomics Applied to Pediatric Asthma: What Have We Learnt in the Past 10 Years?Children (Basel, Switzerland) · 2023Article
- Obesity-related pediatric asthma: relationships between pulmonary function and clinical outcomes.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Application of Metabolomics in Obesity-Related Childhood Asthma Subtyping: A Narrative Scoping Review.Metabolites · 2023Article
- Inverse association between Helicobacter pylori infection and childhood asthma in a physical examination population: a cross-sectional study in Chongqing, China.BMC pediatrics · 2022Article
- The Impact of Dietary Intervention in Obese Children on Asthma Prevention and Control.Nutrients · 2022Review
- Characterizing clinical pediatric obesity subtypes using electronic health record data.PLOS digital health · 2022Article
- A new perspective on cholesterol in pediatric health: association of vitamin D metabolism, respiratory diseases, and mental health problems.Clinical and experimental pediatrics · 2022Article
- Association of Adverse Childhood Experiences Including Low Household Income and Peer Isolation With Obesity Among Japanese Adolescents: Results From A-CHILD Study.Frontiers in public health · 2022Article
- Risk Factors of Childhood Asthma Among Patients Attending a Tertiary Care Centre in North-East India.Journal of asthma and allergy · 2022Article
- 2021 Brazilian Thoracic Association recommendations for the management of severe asthma.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021Review
- Managing Asthma and Obesity Related Symptoms (MATADORS): An mHealth Intervention to Facilitate Symptom Self-Management among Youth.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma is a multifactorial syndrome that threatens the health of children. Body mass index (BMI) might be one of the potential factors but the evidence is controversial. The aim of this study is to perform a comprehensive meta-analysis to investigate the association between asthma and BMI.
methodsElectronic databases including, Web of Science, Pubmed, Scopus, Science Direct, ProQuest, up to April 2017, were searched by two researchers independently. The keywords "asthma, body mass index, obesity, overweight, childhood and adolescence" were used. Random and fixed effects models were applied to obtain the overall odds ratios (ORs) and standardized mean difference (SMD). Heterogeneity between the studies was examined using I
resultsAfter reviewing 2511 articles, 16 studies were eligible for meta-analysis according to inclusion/exclusion criteria. A meta-analysis from 11 case-control studies revealed OR of asthma and overweight as OR = 1.64; (95% Confidence Interval (CI): 1.13-2.38) and from 14 case-control studies, OR for asthma and obesity was OR = 1.92 (95% CI: 1.39-2.65), which indicated that risk of asthma in overweight and obese children and adolescence was significantly higher (1.64 and 1.92 times) than that of individuals with (p-value < 0.01 for underweight/normal weight in both cases). Furthermore, there was a significant relationship between asthma and BMI > 85 percentile according to SMD SMD = 0.21; (95%CI: 0.03-0.38; p-value = 0.021).
conclusionsThe results showed a significant relationship between BMI (obesity/overweight) and asthma among children and adolescents. It is important to study the confounding factors that affect the relationship between asthma and BMI in future epidemiological researches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.