Evidence map›Paper›PMID 29699301›Full record

ArticleReproductive medicine and biology2009

Inhibition of apoptosis by ascorbic and dehydroascorbic acids in

Tomohiro Saitoh, Yuichi Tsuchiya, Toshihiko Kinoshita, Motohiro Itoh, Shigeru Yamashita

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive medicine and biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Tomohiro SaitohDepartment of Obstetrics and Gynecology Toho University Medical Center Sakura Hospital 564-1 Shimoshizu Sakura-shi 285-8741 Chiba Japan.
Yuichi TsuchiyaDepartment of Biochemistry Toho University School of Medicine 5-21-16 Omori-nishi Ota-ku 143-8540 Tokyo Japan.
Toshihiko KinoshitaDepartment of Obstetrics and Gynecology Toho University Medical Center Sakura Hospital 564-1 Shimoshizu Sakura-shi 285-8741 Chiba Japan.
Motohiro ItohDepartment of Obstetrics and Gynecology Toho University Medical Center Sakura Hospital 564-1 Shimoshizu Sakura-shi 285-8741 Chiba Japan.
Shigeru YamashitaDepartment of Biochemistry Toho University School of Medicine 5-21-16 Omori-nishi Ota-ku 143-8540 Tokyo Japan.
Toho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe viability of mammalian eggs after ovulation is reported to be improved by the presence of ascorbic acid in the culture medium. However, the pro-survival mechanisms of ascorbic acid are poorly understood. The molecular pathways of apoptosis are evolutionarily conserved among animal species, and

methodsIncubation of egg extracts for more than 4 h induces the spontaneous release of cytochrome

resultsAscorbic acid showed no effect against cytochrome

conclusionsThe anti-apoptotic effect of ascorbic acid in

Indexed as

ApoptosisAscorbic acidCaspasesDehydroascorbic acidXenopus egg extracts

Identifiers

PMID29699301
PMCPMC5904668
OpenAlexW1993282178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.