ArticleReproductive medicine and biology2013
Effect of long-term caffeine administration to mice on in vitro fertilization and embryo development using oocytes.
Article in Reproductive medicine and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Efficient stem cell-derived mouse embryo models for environmental studies.Developmental cell · 2026Article
- In vitro fertilization embryo development from caffeine-treated murine sperm.Reproductive medicine and biology · 2015Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the effect of long-term caffeine administration to mice on in vitro fertilization (IVF) of oocytes.
methodsMice were injected with different dosages (0, 0.1, and 1.0 mg/mouse/converted day) of caffeine for one month. Subsequently, the fertilization rate and embryo development to blastocyst stage were evaluated in IVF using oocytes from the mice.
resultsThe retrieved average oocyte rate was significantly lower (27.4) in mice injected with 1.0 mg caffeine than in the control group (36.5;
conclusionsOur findings suggest that caffeine administration negatively impacts oocytogenesis and embryonic development after IVF.
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