ArticleClinical biomechanics (Bristol, Avon)2018
The trabecular effect: A population-based longitudinal study on age and sex differences in bone mineral density and vertebral load bearing capacity.
Article in Clinical biomechanics (Bristol, Avon), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- A Viscoelastic Modeling for Failure Analysis of Human Vertebral Bone Undergoing Quasi-Static and Dynamic Compression.Bioengineering (Basel, Switzerland) · 2026Article
- Heterogeneity in Lumbar Segmental Bone Mineral Density and Age-Related Evolution of Whole-Body Bone Mineral Density: Comprehensive Implications for Osteoporosis Risk Assessment.Orthopaedic surgery · 2026Article
- Biomechanical effects of defect size and location on vertebral fracture.Journal of medical and biological engineering · 2025Article
- Intradiscal pressure distributions in degenerated intervertebral discs: A biomechanical investigation.Journal of medical and biological engineering · 2025Article
- Prediction of vertebral failure under general loadings of compression, flexion, extension, and side-bending.Journal of the mechanical behavior of biomedical materials · 2025Article
- Nutrition and Bone Marrow Adiposity in Relation to Bone Health.Physiological research · 2024Review
- Age-related changes in gait, balance, and strength parameters: A cross-sectional study.PloS one · 2024Article
- Article
- CT-based structural analyses of vertebral fractures with polymeric augmentation: A study of cadaveric three-level spine segments.Computers in biology and medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundApproximately 16-24% of postmenopausal women are affected by vertebral fractures, negatively affecting their quality of life. Trabecular and cortical bones in vertebrae decline differently with age, thus having a distinct impact on vertebral failure loads. The purpose of this study was to investigate the effect of trabecular and cortical volumetric bone mineral density loss over time on estimated failure loads; and to evaluate the effect of sex and age.
methodFracture properties from a cohort of 82 patients were evaluated for L
findingsDecline in trabecular and cortical volumetric bone mineral density, and failure load was sex-dependent (p ≤ 0.0095). Cortical and trabecular volumetric bone mineral density reduced 2.08 (g/cm
interpretationTrabecular bone has a significantly greater effect than cortical bone on the structural integrity and load bearing capacity of vertebrae. This might lead to a higher incidence of fragility fractures in osteoporotic women. Our non-invasive, quantitative computed tomography image-based approach may improve prevention, monitoring, and management of fractures.
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