ArticleChest2018
Fixed But Not Autoadjusting Positive Airway Pressure Attenuates the Time-dependent Decline in Glomerular Filtration Rate in Patients With OSA.
Article in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Effects of continuous positive airway pressure on renal function in adults with obstructive sleep apnea: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Meta-analysis of the effects of CPAP therapy on estimated glomerular filtration rate in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Pressure modification or humidification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea.The Cochrane database of systematic reviews · 2019Pooled it
- Prevalence of Urinary Tract Cancer in Patients with Obstructive Sleep Apnea: Data from the Vercelli Registry.Advances in respiratory medicine · 2025Article
- Auto-adjusting positive airway pressure: the fine line between engineering and medicine.Sleep & breathing = Schlaf & Atmung · 2025Review
- Sleep disorders in chronic kidney disease.Nature reviews. Nephrology · 2024Review
- Bidirectional relationships of comorbidity with obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Treatment options in obstructive sleep apnea.Internal and emergency medicine · 2022Review
- Article
- Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithm.Sleep & breathing = Schlaf & Atmung · 2020Article
- Interrelationship among Obstructive Sleep Apnea, Renal Function and Survival: A Cohort Study.International journal of environmental research and public health · 2020Observational
- Burden of Nocturnal Hypoxia and Type of Positive Airway Pressure Therapy May Influence Markers of Acute Kidney Injury in Patients With Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Obstructive Sleep Apnea and Hypertension: Why Treatment Does Not Consistently Improve Blood Pressure.Current hypertension reports · 2019Review
- Comment to the Editorial by KS Park and EW Kang "Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?"Journal of thoracic disease · 2019Article
- Serum levels of NGAL and cystatin C as markers of early kidney dysfunction in patients with obstructive sleep apnea syndrome.Sleep & breathing = Schlaf & Atmung · 2019Article
- Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019Review
- Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?Journal of thoracic disease · 2018Article
Corrections and comments
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Authors and funding
13 authors at 11 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of treating OSA on renal function decline is controversial. Previous studies usually included small samples and did not consider specific effects of different CPAP modalities. The aim of this study was to evaluate the respective influence of fixed and autoadjusting CPAP modes on estimated glomerular filtration rate (eGFR) in a large sample of patients derived from the prospective European Sleep Apnea Database cohort.
methodsIn patients of the European Sleep Apnea Database, eGFR prior to and after follow-up was calculated by using the Chronic Kidney Disease-Epidemiology Collaboration equation. Three study groups were investigated: untreated patients (n = 144), patients receiving fixed CPAP (fCPAP) (n = 1,178), and patients on autoadjusting CPAP (APAP) (n = 485).
resultsIn the whole sample, eGFR decreased over time. The rate of eGFR decline was significantly higher in the subgroup with eGFR above median (91.42 mL/min/1.73 m
conclusionsfCPAP but not APAP may prevent eGFR decline in OSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.