ArticlePloS one2018
Comparison of fruit organic acids and metabolism-related gene expression between Cerasus humilis (Bge.) Sok and Cerasus glandulosa (Thunb.) Lois.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Development and application of KASP molecular marker for accelerated breeding of low-acid Cerasus humilis cultivars.Plant cell reports · 2026Article
- Identification of pivotal genes associated with sugar and organic acid metabolism during Prunus Mume fruit ripening via metabolomic and transcriptomic analyses.BMC plant biology · 2025Article
- Transcriptome Analysis Reveals Distinct Differences in Organic Acid Metabolism Between the Pericarp and the Pulp ofPlants (Basel, Switzerland) · 2025Article
- Relationships Between Organic Acid Metabolism and the Accumulation of Sugars and Calcium in Fruits ofPlants (Basel, Switzerland) · 2024Article
- Preparation ofHeliyon · 2024Article
- Changes in Physicochemical, Free Radical Activity, Total Phenolic and Sensory Properties of Orange (Molecules (Basel, Switzerland) · 2022Article
- Organic acid metabolism in Chinese dwarf cherry [Frontiers in plant science · 2022Article
- Integrated Analysis of the Metabolome and Transcriptome on Anthocyanin Biosynthesis in Four Developmental Stages ofInternational journal of molecular sciences · 2021Article
- Identification of LecRLK gene family in Cerasus humilis through genomic-transcriptomic data mining and expression analyses.PloS one · 2021Article
- Comparative transcriptome analysis reveals key genes potentially related to organic acid and sugar accumulation in loquat.PloS one · 2021Article
- Characterization of Organic Acid Metabolism and Expression of Related Genes During Fruit Development ofPlants (Basel, Switzerland) · 2020Article
- Primary Metabolism in Avocado Fruit.Frontiers in plant science · 2019Review
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5 authors.
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Abstract
Cerasus humilis (Bge.) Sok and Cerasus glandulosa (Thunb.) Lois are economically important fruit-producing shrubs. Although these two species have similar looking fruits, their fruit organic acid contents differ drastically. In this study, we focused on comparing the organic acid content, activity of enzymes gene expression involved in organic acid metabolism in both C. humilis and C. glandulosa fruits. To investigate the differences of organic acid metabolism in fruits of these two species, a comparative transcriptome analysis was performed. Our results showed that temporal changes of two main organic acids exhibited different trends in these two species. Transcriptome sequencing of developing C. humilis and C. glandulosa fruits systematically revealed 6,594 differentially expressed genes. Compared with C. humilis, the expression levels of 3,469 and 3,125 genes were up- and down-regulated in C. glandulosa, respectively, including one PEPC gene, 12 malic acid metabolism genes, 25 citric acid cycle genes, and 194 NAD/NADP metabolism genes. The correlation analysis and principal component analysis of gene expression, enzymatic activity and organic acid content showed that differences in the expression of genes encoding the NAD-malate dehydrogenase (NAD-MDH) and NADP-malate enzyme (NADP-ME) contributed substantially to the observed differences in organic acid accumulation of two species. Our results provide a solid foundation for future elucidation of key mechanisms regulating organic acid biosynthesis in C. humilis and C. glandulosa fruits and could lead to efficient and highly targeted generation of more commercially accepted cultivars.
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