ArticlePloS one2018
Poly(3-hydroxybutyrate) production in an integrated electromicrobial setup: Investigation under stress-inducing conditions.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
- Electrocatalytic COChemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- A Review of Bioelectrochemical Strategies for Enhanced Polyhydroxyalkanoate Production.Bioengineering (Basel, Switzerland) · 2025Review
- Electro-microbial production techno-economic viability and environmental implications.Nature biotechnology · 2025Article
- Autotrophic bacterial production of polyhydroxyalkanoates using carbon dioxide as a sustainable carbon source.Frontiers in bioengineering and biotechnology · 2025Review
- Bio-electrosynthesis of polyhydroxybutyrate and surfactants in microbial fuel cells: a preliminary study.Frontiers in microbiology · 2025Article
- Biohybrid COProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Industrial side streams as sustainable substrates for microbial production of poly(3-hydroxybutyrate) (PHB).World journal of microbiology & biotechnology · 2022Review
- Electroactive biofilms: how microbial electron transfer enables bioelectrochemical applications.Journal of industrial microbiology & biotechnology · 2022Review
- Synthetic biology toolkit for engineering Cupriviadus necator H16 as a platform for COBiotechnology for biofuels · 2021Review
- CyanobacteriumBiotechnology reports (Amsterdam, Netherlands) · 2021Article
- Changes in Cell Size and Shape during 50,000 Generations of Experimental Evolution with Escherichia coli.Journal of bacteriology · 2021Article
- Coupled Electrochemical and Microbial Catalysis for the Production of Polymer Bricks.ChemSusChem · 2020Article
- From COChemSusChem · 2020Article
- L-Amino Acid Oxidases From Mushrooms Show Antibacterial Activity Against the PhytopathogenFrontiers in microbiology · 2020Article
- The Use of a Biopolymer Conjugate for an Eco-Friendly One-Pot Synthesis of Palladium-Platinum Alloys.Polymers · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poly(3-hydroxybutyrate) (PHB), a biodegradable polymer, can be produced by different microorganisms. The PHB belongs to the family of polyhydroxyalkanoate (PHA) that mostly accumulates as a granule in the cytoplasm of microorganisms to store carbon and energy. In this study, we established an integrated one-pot electromicrobial setup in which carbon dioxide is reduced to formate electrochemically, followed by sequential microbial conversion into PHB, using the two model strains, Methylobacterium extorquens AM1 and Cupriavidus necator H16. This setup allows to investigate the influence of different stress conditions, such as coexisting electrolysis, relatively high salinity, nutrient limitation, and starvation, on the production of PHB. The overall PHB production efficiency was analyzed in reasonably short reaction cycles typically as short as 8 h. As a result, the PHB formation was detected with C. necator H16 as a biocatalyst only when the electrolysis was operated in the same solution. The specificity of the source of PHB production is discussed, such as salinity, electricity, concurrent hydrogen production, and the possible involvement of reactive oxygen species (ROS).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.