Evidence map›Paper›PMID 29698022›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2018

Does the cortisol awakening response link childhood adversity to adult BMI?

Kelly F Miller, Reout Arbel, Lauren S Shapiro, Sohyun C Han, Gayla Margolin

Abstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Cortisol, dehydroepiandrosterone, and depressive symptoms as pathways from child abuse to obesity.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Risky Early Family Environment and Genetic Associations with Adult Metabolic Dysregulation.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kelly F MillerDepartment of Psychology.
Reout ArbelDepartment of Counseling and Human Development, University of Haifa.
Lauren S ShapiroDepartment of Psychology.
Sohyun C HanDepartment of Psychology.
Gayla MargolinDepartment of Psychology.

Funding

Adolescents'Exposure to Family and Community ViolenceR01HD046807 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MARGOLIN, GAYLA · 2005 to 2009
$2.1M
Family Violence and Young Adult Dating Aggression: Reactivity and CompassionR21HD072170 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MARGOLIN, GAYLA · 2013 to 2014
$450k
National Institutes of Health; NICHDNational Science FoundationNICHD NIH HHS R01 HD046807NICHD NIH HHS R21 HD072170
6 · The paper itself

Abstract

objectivesChildhood adversity is a risk factor for the development of obesity in adulthood. Dysregulated hypothalamic-pituitary-adrenal (HPA) activity, which has been associated separately with both adverse childhood experiences and obesity, has been posited as a mechanism by which stressful experiences influence body mass index (BMI); however, this mechanism has not yet been tested longitudinally. The present study uses multireporter, longitudinal data across three time points to test whether the adolescent cortisol awakening response (CAR), an index of diurnal HPA activity, mediates the association between adversity in childhood and BMI in adulthood.

methodEighty-two youth, mothers, and fathers reported on adverse childhood experiences from middle childhood to late adolescence. During adolescence, youth provided saliva samples three times each morning across three days, which were assayed for cortisol to calculate CAR. During early adulthood, youth reported height and weight to calculate BMI.

resultsGreater adversity predicted flatter CAR and higher young adult BMI. Flatter CAR partially mediated the association between childhood adversity and young adult BMI.

conclusionsStress-related alterations to HPA activity account in part for the childhood adversity-adult obesity link. Findings are consistent with theoretical models implicating HPA alterations as linking childhood adversity to metabolic and behavioral determinants of BMI in adulthood. (PsycINFO Database Record

Indexed as

Body Mass IndexAdolescentAdultChildChild AbuseFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemLongitudinal StudiesMaleSalivaStress, PsychologicalYoung AdultHydrocortisone

Identifiers

PMID29698022
PMCPMC8041055

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.