ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Comparison of inflammatory markers between brucella and non-brucella epididymo-orchitis.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 17 citations in OpenAlex.
- Retrospective case-control study of haematological indices and inflammatory ratios in the diagnosis of paediatric brucellosis.BMC infectious diseases · 2026Article
- Clinical spectrum and factors associated with Brucella epididymo-orchitis among male patients in a high-endemic region of Northwest China.Frontiers in public health · 2026Article
- Association of Hemoglobin to Red Blood Cell Distribution Width-Standard Deviation (RDW-SD) Ratio and 3-Month Readmission in Elderly Chinese Patients with Heart Failure: A Retrospective Cohort Study.International journal of general medicine · 2023Article
- Brucella prostatic abscess: a retrospective study of eight cases and a literature review.The Journal of international medical research · 2021Review
- Correlation Analysis of Hemoglobin-to-Red Blood Cell Distribution Width Ratio and Frailty in Elderly Patients With Coronary Heart Disease.Frontiers in cardiovascular medicine · 2021Article
- Brucellar reproductive system injury: A retrospective study of 22 cases and review of the literature.The Journal of international medical research · 2020Review
- Usefulness of Blood Parameters for Preliminary Diagnosis of Brucellosis.Journal of blood medicine · 2020Article
- Early predictors ofUrology annalsArticle
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesBrucellosis is a multi-system infectious disease that is associated with inflammation, which causes an increase in acute phase reactants. Hematological inflammatory markers of brucellosis include mean platelet volume (MPV), red cell distribution width (RDW), neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR). In this study, we aimed to evaluate the diagnostic value of hematological inflammatory markers in Brucella epididymo-orchitis (BEO), and to investigate the utility of these markers for differential diagnosis from non-Brucella epididymo-orchitis (non-BEO). MATERIALS AND
methodsWe retrospectively reviewed the records of 22 BEO and 50 non-BEO patients. Hematological parameters were recorded and compared between the two groups. The main diagnostic criteria for BEO were positive clinical findings (i.e., testicular pain, tenderness and scrotal swelling), a positive Rose Bengal test result, standard tube agglutination (STA) titer ≥ 1/160, and/or a positive blood culture.
resultsThe most decisive factors in discriminating between BEO and non-BEO were NLR, RDW, and MPV, in decreasing order of their strength. Regardless of other factors, NLR values < 2.3 significantly increased the odds of BEO (OR=8.080, 95% CI: 1.929- 33.843, p=0.004). After adjusting for other factors, RDW values >14.45% significantly increased the odds of BEO (OR=7.020, 95% CI: 1.749-28.176, p=0.006). Independent of the other factors, patients with MPV < 7.65 fL had a 6.336 times higher risk for BEO (95% CI: 1.393 - 28.822, p=0.017).
conclusionHematological inflammatory markers such as NLR, RDW, and MPV can aid in the differential diagnosis of BEO and non-BEO.
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