Evidence map›Paper›PMID 29697888›Full record

ArticleDepression and anxiety2018

Insomnia mediates the longitudinal relationship between anxiety and depressive symptoms in a nationally representative sample of adolescents.

Y Irina Li, Lisa R Starr, Laura Wray-Lake

Open access · greenAbstract read
In one paragraph

Article in Depression and anxiety, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  13. Hope Buffers the Effect of Fear of COVID-19 on Depression among College Students: Insomnia as a Mediator.International journal of environmental research and public health · 2023
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  14. Changes in telomere length and serum neurofilament light chain levels in female patients with chronic insomnia disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Y Irina LiDepartment of Clinical and Social Sciences in Psychology, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-6143-3940
Lisa R StarrDepartment of Clinical and Social Sciences in Psychology, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-5383-1105
Laura Wray-LakeDepartment of Social Welfare, Luskin School of Public Affairs, University of California, Los Angeles, CA, USA.ORCID 0000-0002-6091-4440
University of Rochester · USUniversity of California, Los Angeles · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

backgroundAnxiety and depression are commonly comorbid with each other, with anxiety often temporally preceding the development of depression. Although increasingly research has begun to investigate the role of sleep problems in depression, no study has examined insomnia as a mediator in the longitudinal relationship between anxiety and subsequent depression.

methodsThe current study utilizes data from Waves I, II, and IV of the National Longitudinal Study of Adolescent to Adult Health, a nationally representative prospective study conducted over a 14-year period (n = 20,745, 50.5% female, M age at Wave I = 16.20). Participants completed portions of the Center for Epidemiologic Studies Depression Scale at Waves I and IV to assess depressive symptoms, a six-item anxiety measure at Wave I, and three items assessing insomnia, sleep quality, and sleep duration at Wave II.

resultsStructural equation modeling indicated that insomnia and unrestful sleep significantly mediated the relationship between anxiety and subsequent depression. The relationship between anxiety and depression was not significantly mediated by sleep duration.

conclusionsFindings suggest that anxiety may increase risk for the development of later depression through insomnia.

Indexed as

AdolescentAdultAnxietyComorbidityDepressionFemaleHumansLongitudinal StudiesMaleSleep Initiation and Maintenance DisordersUnited Statesanxiety/anxiety disorderschild/adolescentdepressionmood disorderssleep disorders

Identifiers

PMID29697888
PMCPMC5992096
OpenAlexW2799904575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.